Helium, the lightest noble gas, is a valuable resource located on the Colorado Plateau southwestern US. Helium, a proven, useful noble gas, has many applications in modern technology for its chemical, physical, and thermodynamic properties. As of this writing, the price of crude helium is ~40% greater than CH 4 , rendering the economic grade for direct and secondary extraction at 0.3% helium. The helium systems in the Four Corners area (i.e., the study area) are characterized utilizing the geochemistry of noble gases, hydrocarbons, and nonhydrocarbons (compositional and isotopic), as well as geologic mapping. The geochemistry delineates sources of gases, migration pathways, and potential trapping/sealing mechanisms of the helium system, which is a slight deviation from the petroleum system. Economic helium (>0.3%) is primarily found in Paleozoic intervals structurally trapped on the Four Corners Platform, the edge of the Defiance Uplift, and the edge of the Holbrook Basin. Thirty-one gas samples, isotopically analyzed, are from actively producing Paleozoic formations within five fields: Tocito Dome, Dineh-Bi-Keyah, Ratherford, Pinta Dome, and Navajo Springs. Helium concentrations range from 0.01% to >6.0% and incorporates a spectrum of other gas values associated with relatively similar Paleozoic formations.