The results of the palynological analysis and 14 C dating of the most complete sequences of the Holocene sediments were used for a detailed reconstruction of multi-cyclic alternations of climate phases and zonal and intrazonal plant formations that were taking place the Lower Volga region during the last ten thousand years. Twenty-six phases in evolution of the natural environment during the Holocene were distinguished. Landscape-climatic characteristics and chronological boundaries were identified for these phases. Reconstructed paleoclimatic stages were correlated to the Holocene transgressions and regressions in the Caspian Sea region. The model developed for periodization of climatic events may serve as a climato-stratigraphical framework for future paleogeographical studies of the Holocene in the Northern Caspian region.KEY WORDS: the Lower Volga region, Holocene, pollen assemblages, 14 C dating, vegetation and climate reconstructions, paleo-environments, transgressions and regressions of the Caspian Sea