The recovery of free chlorambucil from solution in blood serum

Eradication of Murine Lymphoma and Melanoma Cells by Chlorambucil‐Antibody Complexes

“…The active and hydrolized forms of chlorambucil in the complexes were measured by a method described by Linford (1962).…”

“…The amount of chlorambucil was determined from the absorbance at 258 nm after correction for scattering (Linford 1962). The absorbance of the dissolved residues was measured with the spectrophotometer in the region 230-280 nm with continuous scanning.…”

“…The absorbance of the dissolved residues was measured with the spectrophotometer in the region 230-280 nm with continuous scanning. The amount of chlorambucil was determined from the absorbance at 258 nm after correction for scattering (Linford 1962). As a reference, a solution of 30 mg chlorambucil/ml ethanol was used with an absorbance of 1.55 corrected for scattering.…”

Mass Spectrometry of Chlorambucil, its Degradation Products, and its Metabolite in Biological Samples

“…Evidence has accumulated that the aminothiol protecting agents cause a temporary inhibition of nucleoprotein synthesis and facilitate repair of radiation damage (2)(3)(4)(5), but the necessity for complexation in this process has not been shown. Evidence has accumulated that the aminothiol protecting agents cause a temporary inhibition of nucleoprotein synthesis and facilitate repair of radiation damage (2)(3)(4)(5), but the necessity for complexation in this process has not been shown.…”