The Recurrent Basal Cell Epithelioma

Menn, Henry

doi:10.1001/archderm.1971.04000180054007

Cited by 143 publications

(32 citation statements)

References 5 publications

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“…There are few studies which have analyzed BCCs recurring after surgery. Menn et al [13] described a ‘change from solid nests of tumor cells within mucinous stroma to infiltrating elements embedded in a dense connective stroma tissue’. By the same histopathological criteria used in our study, Boulinguez et al [14] described aggressive recurrences in 4 of 20 (20%) superficial or nodular BCCs.…”

Section: Discussionmentioning

confidence: 99%

Facial Basal Cell Carcinomas Recurring after Photodynamic Therapy: A Retrospective Analysis of Histological Subtypes

et al. 2012

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Background: Photodynamic therapy (PDT) is an established treatment for basal cell carcinomas (BCCs). Although recurrences are sometime observed, their histological patterns have never been specifically studied or compared with the one of the initial tumor. Objective: To compare the histopathological aggressiveness of BCCs recurring after PDT with that of the primary tumors. Methods: The study population included 12 patients with 16 post PDT recurrent BCCs. Outcome measures were proportion of histologically aggressive subtypes in BCC recurrences vs. primary tumor. Results: 62.5% of recurrent BCCs displayed a transition from a non-aggressive to an aggressive subtype. Conclusions: Post PDT recurrences appear to display an increased histological aggressiveness, although the latter may reflect the natural course of tumor progression. Despite the presence of potential biases, our study raises the possibility that PDT favors the selection of more aggressive tumor cells. Better systematic large-scale follow-up studies are required to assess the exact frequency and histological types of BCC recurrences after PDT.

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Section: Discussionmentioning

confidence: 99%

Facial Basal Cell Carcinomas Recurring after Photodynamic Therapy: A Retrospective Analysis of Histological Subtypes

et al. 2012

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“…The corresponding num¬ ber of the tissue section is placed on the correct square and given to the technician who adds formaldehyde solution. The tis¬ sue is briefly fixed in the formaldehyde so-Accepted for publication April 1,1974 lution, flattened as in classical chemo¬ surgery, and then processed by cryostat microtome technique. The sections are cut from their inferior surface and arranged on frosted slides in a line with the inferiormost cut at one end and the superior-most cut at the opposite end.…”

Section: Methodsmentioning

confidence: 99%

Microscopically Controlled Excision of Skin Tumors

Tromovitch¹,

Stegeman²

1974

Arch Dermatol

196

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“…Em 90% dos casos, a recidiva ocorreu dentro de urn periodo p6s-operat6rio de 24 meses ((MENN et al, 1971). A simples ocorrencia desta recidiva denotaria maior agressividade tumoral.…”

Section: -----------------------------1 1ntrodu~ao 16unclassified

“…A simples ocorrencia desta recidiva denotaria maior agressividade tumoral. MENN et al (1971) trataram 100 doentes com CBCs recidivados, observando uma nova recidiva em 47%. Num outro estudo em CECs, houve nova recidiva em 23,3% e aparecimento de metastases em 30,3% dos casos (ROWE et al, 1992 …”

Section: -----------------------------1 1ntrodu~ao 16unclassified

“…0 tempo de seguimento mediano do Grupo 3 foi de 36 meses, nao diferindo estatisticamente do primeiro grupo. Como ja foi mencionado, a ausencia comprovada de recidiva nestes doentes neste periodo tornava bastante precisa a caracterizac;ao dos tumores deste grupo como de evoluc;ao favoravel, pela possibilidade muito remota de aparecimento da recorrencia tumoral ap6s 24 meses (MENN et al, 1971).…”

Section: Seguimento E Evoluunclassified

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Carcinomas cutâneos com acometimento suspeito ou comprovado da base do crânio: fatores clínicos, histopatológicos e biológicos

Cernea¹

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As Dras. lnes de Castro e Miriam N. Sotto, pela perseveran<_;a demonstrada na obten<_;ao dos blocos anatomopatol6gicos dos casos deste estudo, pela leitura das laminas, que foi pe<_;a fundamental desta pesquisa, e pela confec<_;ao das laminas em branco para a analise imunohistoquimica.Ao Prof. Dr. Carlos E. Bacchi e Dra. Angela F. Logullo, pela inestimavel contribui<_;ao para o planejamento da analise imunohistoquimica, pelo auxilio na pesquisa da gigantesca literatura sobre o assunto e pela execu<_;ao e leitura das avalia<_;6es imunohistoquimicas que constituiram uma das bases deste estudo . A Srta. Mariana Curi, pela competencia na execu<_;ao da analise estatistica desta tese.As Sras. Valeria V. Lombardi, Mariaceu P. Faria e Rogeria C. Dias pela eficiencia na obten<_;ao das referencias bibliograticas no Brasil e no Exterior.A Sra. Sonia L. P. T. Carvalho pela elabora<_;ao da ficha catalogratica da tese. Aos doentes que colaboraram para que esta tese se tornasse possivel e que sao, em ultima ancilise, a razao primeira de nossas carreiras profissionais, pois todos n6s almejamos, ao nos aprimorarmos, oferecer-lhes urn cuidado medico cada vez mais competente e eficaz, a minha respeitosa homenagem.Finalmente, gostaria de agradecer aqueles que tenham contribuido para a feitura desta tese e que, por alguma infeliz omissao de minha parte, nao foram aqui lembrados.

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The Recurrent Basal Cell Epithelioma

Cited by 143 publications

References 5 publications

Facial Basal Cell Carcinomas Recurring after Photodynamic Therapy: A Retrospective Analysis of Histological Subtypes

Facial Basal Cell Carcinomas Recurring after Photodynamic Therapy: A Retrospective Analysis of Histological Subtypes

Microscopically Controlled Excision of Skin Tumors

Carcinomas cutâneos com acometimento suspeito ou comprovado da base do crânio: fatores clínicos, histopatológicos e biológicos

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