The Red Cell Antigen Pk and its Relationship to the
P System: the Evidence of Three More P^k Families

Kortekangas, A.E.; Kaarsalo, E.; Melartin, Liisa; Tippett, Patricia; Gavin, June; Noades, Jean; Sanger, Ruth; Race, R.R.

doi:10.1159/000465021

Cited by 12 publications

(22 citation statements)

References 6 publications

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“…Some Luke(-) members lacking Pk were found in one of the latter families. The Luke reactions of these Pk families are not given here, for they will be taken into account against the background of the larger problem of Pk [1].…”

Section: Propositusmentioning

confidence: 99%

An Agglutinin Associated with the P and the ABO Blood Group Systems

et al. 1965

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Section: Propositusmentioning

confidence: 99%

An Agglutinin Associated with the P and the ABO Blood Group Systems

et al. 1965

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“…The haemagglutination reactions of LM 147/328 monoclonal antibody are in accord with reactions ascribed to human anti-P [9][10][11]. Characterization of the microbial agent responsible for the murine antibody is currently in progress.…”

Section: Discussionmentioning

confidence: 75%

Serological Characterisation of a Mouse Monoclonal Anti-P-Like Antibody

Inglis¹,

Fraser²,

Mitchell³

et al. 1987

Vox Sanguinis

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An IgM mouse monoclonal antibody, LM 147/328, raised against an Escherichia coli immunogen, was found to possess anti-P-like specificity. It is proposed that this antibody recognises an epitope on a Ga1β1-3GalNAc disaccharide structure (GalNAc = N-acetyl-D-galactosamine). The haemagglutinating activity of this antibody was consistently strong with adult erythrocytes, but gave significantly weak reactions with about 7% of cord erythrocyte samples.

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“…In the first pattern, the gene is restricted to the areas settled first, such as Afinn. This kind of distribution is seen in blood group Pk [7,12], transferrin variant Dfui [12,18], blood group En(a-) [4], and X-linked retinoschisis [3]. The other alternative is that the gene is found sporadically in one or more areas, including several present parishes which represent original superisolates.…”

Section: The Distribution Of Other Marker Genes In Finlandmentioning

confidence: 99%

An Inherited Blood Group A Variant in the Finnish Population

Nevanlinna¹,

Pirkola²

1973

Vox Sanguinis

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A rare variant of blood group A, A(finn), is used as a marker when studying the Finnish population structure. Slow immigration is probably the main cause of the primary enrichment of this gene that has not yet been described outside Finland.Practically all the 98 propositi originated from the areas in the south-west and south-east that were first settled in prehistoric times. This indicates that both were inhabited by the same settlers, probably immigrating over the Gulf of Finland rather than using two different routes. The frequency of A(finn) in the first settled areas was estimated at approximately 1:1,000, showing large local differences at community level, with estimated peaks as high as more than 1%. The frequency distribution was analysed in a computer simulation programme; the similarities with the observed distribution of A(finn) were compatible with the effect of sampling and drift, causing substantial loss and large frequency deviations in the isolated subpopulations.

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The Red Cell Antigen Pk and its Relationship to the P System: the Evidence of Three More P^k Families

Cited by 12 publications

References 6 publications

An Agglutinin Associated with the P and the ABO Blood Group Systems

An Agglutinin Associated with the P and the ABO Blood Group Systems

Serological Characterisation of a Mouse Monoclonal Anti-P-Like Antibody

An Inherited Blood Group A Variant in the Finnish Population

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