The reduction in the detection of melanoma during the coronavirus disease 2019 (COVID-19) pandemic in a melanoma center of South Italy

Public interest in dermatologic symptoms, conditions, treatments, and procedures during the COVID‐19 pandemic: Insights from Google Trends

“…17 Moreover, studies from Italy showed a statistically significant increase in mean Breslow thickness during the post-lockdown phase compared with the pre-lockdown and decreased detection of melanoma during the COVID-19 pandemic. 18,19 Another study from the United Kingdom has reported that the NMSCs excised in 2020 required significantly larger and more complex surgery than in 2019. 20 Altogether, these findings suggest an increased delay in the diagnosis of skin cancers, which in turn might result in more advanced disease requiring more complex surgical procedures.…”

“…In fact, a recent report from the United Kingdom has shown a decrease up to 47% in the number of non‐melanoma skin cancer treated and melanoma patients undergoing sentinel lymph node biopsies 17 . Moreover, studies from Italy showed a statistically significant increase in mean Breslow thickness during the post‐lockdown phase compared with the pre‐lockdown and decreased detection of melanoma during the COVID‐19 pandemic 18,19 . Another study from the United Kingdom has reported that the NMSCs excised in 2020 required significantly larger and more complex surgery than in 2019 20 .…”

“…The coronavirus disease 2019 (COVID- 19), a novel infectious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged in December 2019. The rapid and worldwide spread of the disease led to the declaration of a pandemic by WHO in March 2020.…”

Ribonucleic acid COVID‐19 vaccine‐associated cutaneous adverse drug events: a case series of two patients

“…Bonetto et al reported influenza vaccination as the vaccine type most likely to trigger vasculitis, particularly the cutaneous vasculitis subtype. 4 Our case series suggest that the mechanism of vaccine-associated cutaneous ADEs may not be dependent upon vaccine uptake by antigen-presenting cells, as is the case for live or inactivated vaccines. Understanding downstream transcriptomics-related events following drug administration (including vaccination) could potentially be useful in the identification of individuals at risk of experiencing ADEs.…”

“…Stopping the causative drug, applying topical steroids and whitening agents, and waiting for spontaneous recovery are options. 4 If lesions persist in such cases, laser therapy is probably recommended as the most effective method. 5 Topical bleaching agents have poor efficacy in the treatment of pigmentation arising from fixed drug eruptions.…”