Abstract-Traditional compression algorithms of OFDM signals with a low compression ratio and a low SNR come along with a high error rate, which fail to meet the requirements of OFDM systems. To achieve high compression ratio and low error rate, we propose a new algorithm based on a combination of clipping with tail plug (CTP) and partial sample calibration (PSC). The new algorithm can achieve the nearly loss-less compression and the compression ratio can be as high as 1.86:1 with a error rate less than 10^(-7), while SNR corresponding to quantization error is up to 70dB in 4096-QAM OFDM signal modulation schemes, which meets well for the requirements of the FTTdp+GDSL systems.