The regulatory and scientific approach to defining gum arabic (Acacia senegal and Acacia seyal) as a dietary fibre

Phillips, Glyn O.; Ogasawara, Takashi; Ushida, Kazunari

doi:10.1016/j.foodhyd.2006.12.016

Cited by 94 publications

(48 citation statements)

References 49 publications

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“…A few reports (Cherbut et al 2003;Calame et al 2008) indicate that gum acacia is able to selectively raise the proportions of LAB and bifidobacteria in healthy subjects. Therefore, it was considered as a prebiotic dietary fibre (Phillipsa et al 2006). There is evidence that gum feeding can not only improve intestinal transit and provide digestive comfort (Cherbut et al 2003) but also produce less abdominal side effects than FOS (Goetze et al 2008).…”

Section: Growth Of Lactobacilli Cultures In Presence Of Prebioticsmentioning

confidence: 99%

Development of freeze dried synbiotic formulation using a probiotic strain of Lactobacillus plantarum

2011

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Synbiotics offer potential in the prophylactic management of gastrointestinal disorders. Therefore, present study evaluates the effect of prebiotics (inulin and gum acacia) on Lactocaillus plantarum for developing a freezedried synbiotic product from the selected culture. L. plantarum exhibited the highest specific growth rate (0.23/h) in presence of inulin followed by gum acacia (0.22/h) and glucose (0.22/h). Preparation of the lyophilized synbiotic powder incorporating inulin or gum acacia and using non fat dry milk as base material was standardized. Throughout refrigerated storage for 90 days, viable counts (i. e. 8 to 9 log cfu/g) of the probiotic bacteria in the product remained high, while a considerable reduction in the counts was observed in the product stored at room temperature (25±1°C).

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Section: Growth Of Lactobacilli Cultures In Presence Of Prebioticsmentioning

confidence: 99%

Development of freeze dried synbiotic formulation using a probiotic strain of Lactobacillus plantarum

2011

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“…Dietary fibers are naturally found in horticultural products, fruits, whole grain, legumes, and seeds (INSTITUTE OF MEDICINE, 2001), and they are widely recommended due to their properties related to improving health. Nowadays, they are classified as functional food due to their beneficial effects on human body, such as lowering blood cholesterol, cancer prevention, increase in intestinal function, intervention in the metabolism of lipids, and carbohydrates, and in the physiology of the gastro intestinal tract (DE VRIES, 2004;PHILLIPS et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Development and chemical characterization of flour obtained from the external mesocarp of "pequizeiro" fruit

Júnior¹,

Bassinello²,

Caliari³

et al. 2010

Ciênc. Tecnol. Aliment.

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“…6 No adverse effects were recorded after AG use even at very high doses. 7 Intestinal bacteria fermentation transforms Arabic gum to fatty acids that is considered a prebiotic. It prevents glucose absorption, and so reduce plasma glucose by elevating the insulin secretion.…”

Section: Introductionmentioning

confidence: 99%

Arabic gum acacia improves diabetic peripheral neuropathy in rats: a biochemical and histopathological evidence

Almohaimeed

Amin

El-Aziz

et al. 2018

Int J Basic Clin Pharmacol

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INTRODUCTIONDiabetes mellitus (DM) is thought to be a noteworthy risk to public health. Data from the World Health Organization (WHO) showed that almost half of all deaths attributable to high blood glucose occur before the age of 70 years. WHO projects that diabetes will be the seventh leading cause of death in 2030. 1 Diabetic peripheral neuropathy (DPN) is a frequent complication of diabetes mellitus.Studies conducted in the Middle East revealed high rates of DPN ranged from 35% to 65%. The DPN is more frequently represented than other complications of Diabetes Mellitus. It was reported that it is responsible for 50%-75% of non-traumatic amputations. Painful DPN has high grade of functional disability which influences health-related quality of life. 2 Hyperglycemia is basic for occurrence and advancement of DPN with the etiological hypotheses on metabolic or vascular causes. 3 Regardless of numerous investigations on DPN, the present ABSTRACT Background: Diabetic peripheral neuropathy (DPN) is a frequent complication of diabetes mellitus and unfortunately, its present therapeutic alternatives are exceptionally poor. Objectives of this study was to assess the antidiabetic, antioxidant and hypolipidemic action of Gum Arabic (GA) and its role in promoting the functional recovery from diabetic neuropathy developed in in an experimental model of diabetic neuropathy. Methods: Sixty adult male Sprague-Dawley rats were utilized and randomly assigned into six groups (n= 10); control, Arabic gum-treated, untreated diabetic, diabetic received metformin, diabetic received metformin and B12 vitamin and diabetic received metformin, B12 vitamin and AG. Locomotor activity and hyperalgesia were assed at the end of the study. Fasting and two hours postprandial blood glucose, serum insulin levels, lipid Profile, oxidants/antioxidants parameters were assessed in the blood. Sciatic nerve was assessed histopathologically. Results: The locomotor activity of the untreated diabetic rats was significantly (p<0.001) reduced compared to the control group while it was significantly increased in all treated groups. The lipid profile and Malondialdehyde were significantly improved in all treated groups. Levels of CAT, GSH, SOD, GPx were significantly decreased in untreated diabetic group compared to the control while they were significantly increased in all treated groups compared to the untreated diabetic group. Sciatic nerve fibers of untreated diabetic rats showed degenerated axons with dilated myelin sheaths and degenerated Schwann cells. The nerve had significantly fewer fiber compared to the control. These changes were alleviated in all the treated groups specifically that received metformin, vitamin B12 and GA. Conclusions: It could be concluded that Arabic gum had hypoglycemic, antioxidant and hypolipidemic activity and had a protective effect on diabetic neuropathy. Based on this it is recommended that human clinical trials are necessary to prove this therapeutic effect.

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The regulatory and scientific approach to defining gum arabic (Acacia senegal and Acacia seyal) as a dietary fibre

Cited by 94 publications

References 49 publications

Development of freeze dried synbiotic formulation using a probiotic strain of Lactobacillus plantarum

Development of freeze dried synbiotic formulation using a probiotic strain of Lactobacillus plantarum

Development and chemical characterization of flour obtained from the external mesocarp of "pequizeiro" fruit

Arabic gum acacia improves diabetic peripheral neuropathy in rats: a biochemical and histopathological evidence

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