The Relation of Psychological Stress to Pregnancy Outcome Among Women Undergoing In-Vitro Fertilization and Intracytoplasmic Sperm Injection

Gourounti, Kleanthi; Anagnostopoulos, Fotios; Vaslamatzis, Grigoris

doi:10.1080/03630242.2011.574791

Cited by 57 publications

(50 citation statements)

References 47 publications

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“…The Fertility Problem Inventory (FPI) was developed in 1999 as a specific measure of infertility-related stress in males and females [54] and has been utilised in a number of interventional studies [35, 37, 41, 42]. The FPI was developed through a qualitative literature review to inform the underlying concepts [54].…”

Section: Resultsmentioning

confidence: 99%

A review of patient-reported outcome measures to assess female infertility-related quality of life

Kitchen¹,

Aldhouse²,

Trigg³

et al. 2017

Health Qual Life Outcomes

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BackgroundInfertility has a negative impact on quality of life (QoL) and well-being of affected individuals and couples. A variety of patient-reported outcome (PRO) measures to assess infertility-related QoL are available; however, there is a concern regarding potential issues with their development methodology, validation and use. This review aimed to i) identify PRO measures used in infertility interventional studies ii) assess validation evidence to identify a reliable, valid PRO measure to assess changes in QoL or treatment satisfaction in clinical studies with female patients following treatment with novel therapies iii) identify potential gaps in evidence for validity.MethodsA structured literature search of Medline, Embase, and the Cochrane Library (accessed in September 2015) was conducted using pre-defined search terms. The identified publications were reviewed applying eligibility criteria to select interventional female infertility studies using PROs. Infertility-specific PRO measures assessing QoL, treatment satisfaction or psychiatric health, and included in studies by ≥2 research groups were selected and critically reviewed in light of scientific and regulatory guidance (e.g. FDA PRO Guidance for Industry) for evidence of content validity, psychometric strength, and patient acceptability.ResultsThe literature search and hand-searching yielded 122 publications; 78 unique PRO measures assessing QoL, treatment satisfaction or psychiatric health were identified. Five PRO measures met the selection criteria for detailed review: Fertility Quality of Life (FertiQoL); Fertility Problem Inventory (FPI); Fertility Problem Stress (FPS); Infertility Questionnaire (IFQ); Illness Cognitions Questionnaire adapted for Infertility (ICQ-I). None of the PRO measures met all validation criteria. The FertiQoL was the most widely used infertility-specific PRO measure to assess QoL in interventional studies, with reasonable evidence for adequate content validity, psychometric strength, and linguistic validation. However, gaps in evidence remain including test-retest reliability and thresholds for interpreting clinically important changes. While the FPI demonstrated reasonable evidence for content and psychometric validity, its utility as an outcome measure is limited by a lack of recall period.ConclusionThe FertiQoL and the FPI are potentially useful measures of infertility-related QoL in interventional studies. Further research is recommended to address gaps in evidence and confirm both PRO measures as reliable assessments of patient outcomes.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-017-0666-0) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

A review of patient-reported outcome measures to assess female infertility-related quality of life

Kitchen¹,

Aldhouse²,

Trigg³

et al. 2017

Health Qual Life Outcomes

View full text Add to dashboard Cite

show abstract

“…14 Gourounti et al, argue that the increasing level of anxiety and infertility distress during treatment has a negative influence on pregnancy rates. 15 It has been reported that anxiety increases in the infertility treatment process 5 and decreases with the use of effective coping methods. 16 According to Pasch, the most important point to be taken into account to decrease anxiety in the infertility treatment process and in case of failure of the treatment is not only to prepare patients for the infertility treatment process and for the possible failure of the treatment, but also to help them cope with this effectively.…”

Section: Introductionmentioning

confidence: 99%

Effects of Nursing Care Based on Watson’s Theory of Human Caring on Anxiety, Distress, And Coping, When Infertility Treatment Fails: A Randomized Controlled Trial

Ozan¹,

Okumuş²

2017

J Caring Sci

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Introduction: The failure of infertility treatment leads to individual, familial, and social problems. The objective of this study was to evaluate the effectiveness of the nursing care program based on Watson’s "Theory of Human Caring" on anxiety and distress caused by coping when the treatment fails. Methods: This study randomized controlled trial study was conducted from April to November 2012, with 86 Turkish women with infertility (intervention group: 45, control group: 41). Follow-up of 32 infertile women, who failed infertility treatment from intervention group, and 35 infertile women, who failed infertility treatment from control group, continued for another four weeks. Data were collected through Spiel Berger’s State/Trait Anxiety Inventory, Distress Scale, and Ways of Coping Questionnaire. The analyses of data were conducted using SPSS ver 13. Results: The intervention and control groups significantly differed in terms of anxiety, distress, and coping levels. The intervention group’s mean anxiety score decreased by thirteen points and distress by fourteen points (in a positive direction). The intervention group’s mean positive coping style score increased. Whereas a negative increase was observed in the control group’s values depending on the failure of the treatment. Conclusion: Watson’s theory of human caring is recommended as a guide to nursing patients with infertility treatment to decrease levels of anxiety and distress, and to increase the positive coping style among infertile women.

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“…Recently, researchers and clinicians have shown that psychological factors might reduce the chances of achieving pregnancy with IVF [3–5]. Previous studies have revealed a possible association between stress and reproductive outcomes.…”

Section: Introductionmentioning

confidence: 99%

The effect of fertility stress on endometrial and subendometrial blood flow among infertile women

Yan

Cai

Xing

et al. 2017

Reprod Biol Endocrinol

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BackgroundTo investigate the effect of fertility stress on endometrial and subendometrial blood flow among infertile women.MethodsThis case–control study was conducted in The First Affiliated Hospital of Zhengzhou University. The fertility problem inventory (FPI) was adopted to evaluate fertility stress. Three-dimensional power Doppler ultrasonography (3D PD-US) was performed during the proliferative phase of the menstrual cycle (days 5–11) to measure endometrial thickness, pattern, endometrial and subendometrial volume (V), the vascularization index (VI), the flow index (FI) and the vascularization-FI (VFI) index. Then, 300 infertile women were separated into two groups (high-score group and low-score group) based on total FPI scores and 80 healthy women were selected as controls.ResultsNo differences were found among all three groups with regard to general characteristics, endometrial thickness, pattern, endometrial and subendometrial V, VI and VFI. The endometrial and subendometrial FIs associated with different stress levels significantly differed among the three groups (F = 33.95, P < 0.001; F = 44.79, P < 0.001, respectively). The endometrial and subendometrial FIs in the control group were significantly higher than those in the high-score group and low-score groups. The endometrial and subendometrial FIs in the low-score group were significantly higher than those in the high-score group. The total FPI score was closely related to the endometrial and subendometrial FIs (r = −0.304, P < 0.001; r = −0.407, P < 0.001, respectively).ConclusionFertility stress was associated with endometrial and subendometrial flow index. Whether fertility stress might affect pregnancy outcome by reducing endometrial and subendometrial blood flow requires further research.

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The Relation of Psychological Stress to Pregnancy Outcome Among Women Undergoing In-Vitro Fertilization and Intracytoplasmic Sperm Injection

Cited by 57 publications

References 47 publications

A review of patient-reported outcome measures to assess female infertility-related quality of life

A review of patient-reported outcome measures to assess female infertility-related quality of life

Effects of Nursing Care Based on Watson’s Theory of Human Caring on Anxiety, Distress, And Coping, When Infertility Treatment Fails: A Randomized Controlled Trial

The effect of fertility stress on endometrial and subendometrial blood flow among infertile women

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