The Relation of the Kidney to Body Growth and to the Utilization of Protein and Urea–Parti. Effects of Subtotal Nephrectomy on the Growth of Rats on Diets with and without Urea Supplementation

Abstract

Part I. Effects of Subtotal Nephrectomy on the Growth of Rats on Diets with and without Urea SupplementationSubtotally nephrectomized rats, in contrast to normal rats, show impaired growth rates when urea is added to low protein diets. It is suggested that an intact kidney is necessary for the utilization of urea in growth and further that the kidney serves as one limiting determinant of the extent of protein utilization.