This article summarizes a symposium organized and cochaired by Maria Testa and presented at the 2005 Annual Meeting of the Research Society on Alcoholism, in Santa Barbara, California. The symposium explored issues relevant to understanding the function of placebo conditions and to interpreting placebo effects. Cochair Mark Fillmore began with an overview of the use of placebo conditions in alcohol research, focusing on methodological issues. Jeanette Norris and her colleagues conducted a review of studies examining placebo conditions among women. They conclude that expectancy effects are limited to a few domains. Maria Testa and Antonia Abbey presented papers suggesting that placebo manipulations may result in unanticipated compensatory effects in actual or hypothetical social situations. That is, placebo participants may compensate for anticipated cognitive impairment through vigilant attention to situational cues. John Curtin's research suggests that the compensatory strategies of placebo participants appear to involve a sensitization of evaluative control, resulting in improved performance. Kenneth Leonard provided concluding remarks on the meaning of placebo effects and the value of placebo conditions in research.
KeywordsAlcohol Drinking; Placebo Effect; Methods THE PLACEBO EFFECT is intimately tied to the concept of expectancy that arose out of the need to specify an internal (i.e., cognitive) representation of the learning experience (Bolles, 1972;Tolman, 1932). When an association between 2 events is learned, the first event is said to elicit an expectancy of the second event. Moreover, once learned, the expectancy itself can elicit the associated outcome, and thus expectancies are considered to be an important determinant of behavior (Kirsch, 1999).The placebo has a long history as a control-comparison condition in studies of drug effects on behavior (Kirsch, 1999). Early medical reports of the beneficial effects of placebos led to considerable interest beyond their use as control conditions. In particular, the placebo effect