The Relationship between Dental Caries and Tooth Enamel Fluoride

Mellberg, J.R.; Ripa, Louis W.; Leske, Gary S.; Sanchez, M.; Polanski, R.

doi:10.1159/000260871

Cited by 17 publications

(15 citation statements)

References 10 publications

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“…In another study no significant association between the F concentration in surface enamel and den tal caries was obtained but significant in verse correlations between DM FT and the F concentrations in the subsurface enamel layers were recorded [Schamschula et al, 1979). A significant but weak correlation between enamel F concentration and den tal caries experience was reported by several other investigators [Keene et al, 1973;DePaola et al, 1975;Speake et al, 1979;Spector and Curzon, 1979;Keene et al, 1980;Mellberg et al, 1985). A signifi cant positive association between dental caries experience (expressed as square root DM FT) and enamel F concentration (expressed as loge mass F) was obtained in 14-to 16-year-old children residing in a high fluoride area [Retief et al, 1979b],…”

mentioning

confidence: 86%

Relationship between Enamel Fluoride Concentration and Dental Caries Experience

1987

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Enamel biopsies for F analysis were performed on the mesial, buccal, distal and lingual surfaces of contralateral pairs of premolars extracted from 104 10- to 14-year-old children. Five successive etchings, each of 5 s duration, were carried out on the mesial and buccal surfaces with 2 M HClO₄, and 5 successive etchings, each of 2 s duration, were performed on the distal and lingual surfaces using 0.5 M HClO₄. The F concentrations were adjusted to standardized depths and the F concentrations at individual and cumulative etch depths determined. The caries experience of the children was expressed as filled teeth (FT) or filled surfaces (FS). Highly significant correlations (p = 0.0001) between age and FT and FS were obtained. No significant relationship between dental caries experience and enamel F concentration was established in the present study except for a significant correlation between dental caries and the enamel F concentration in the outermost 10 μm on the buccal aspects of the premolar teeth.

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confidence: 86%

Relationship between Enamel Fluoride Concentration and Dental Caries Experience

1987

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“…Such high concentrations could not be reached in surface layers of individuals from non-fluoridated areas. In a study of 215 subjects aged 14-24 years, where most of the subjects (83%) were from fluoride-deficient areas, Mellberg et al [1985] found a small but significant correlation between enamel fluoride at 1 and 3 m depths and DMFS of individual subjects. This study demonstrated that caries and enamel fluoride were inversely related even though the correlation was weak.…”

Section: Pre-eruptive Fluoridementioning

confidence: 96%

Effects of Water Fluoride Exposure at Crown Completion and Maturation on Caries of Permanent First Molars

Singh

Spencer²,

Brennan³

2006

Caries Res

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Pre-eruptive fluoride exposure has been shown to be important for caries prevention. This paper aimed to determine the relative effects of water fluoride exposure during crown completion (CC) and maturation on caries experience in first permanent molars. Parental questionnaires covering residential history were linked to oral examinations of 19,885 6- to 15-year-old Australian children conducted in 1992 by the School Dental Services of South Australia and Queensland. The percentage of lifetime exposed to optimally fluoridated water at CC, maturation (MAT) and post-eruption (POST) was calculated. Combined exposure variables describing different levels of CC, maturation and post-eruption were created using a threshold exposure of 50%. Compared to the reference of CC <50%/MAT <50%/POST <50%, the categories CC ≧50%/MAT <50%/POST ≧50% [rate ratio (RR) 0.52], CC ≧50%/MAT ≧50%/POST <50% (RR 0.61) and CC ≧50%/MAT ≧50%/POST ≧50% (RR 0.67) had the strongest caries-preventive effect, followed by CC ≧50%/MAT <50%/POST <50% (RR = 0.79) and CC <50%/MAT ≧50%/POST ≧50% (RR = 0.81) in negative binomial regression models (p < 0.05). The categories CC <50%/MAT ≧50%/POST <50% (RR = 0.85) and CC <50%/MAT <50%/POST ≧50% (RR = 0.84) had weaker, non-significant caries-preventive effects. In conclusion a high exposure at CC was important for caries prevention irrespective of the effect of exposure at maturation and post-eruption. The strongest caries-preventive effect was produced by a high exposure at CC supplemented by a high exposure at maturation and/or post-eruption, but the latter two phases could not produce a significant caries-preventive effect on their own. Since most of the caries occurred on pit and fissure surfaces, the findings relate to this class of lesion.

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“…Monofluorophosphate (MFP) has been shown to be an efficacious agent against caries [Mellberg and Ripa, 1983]. The anticaries effect of MFP derives from a complicated set of concomitant interactions at the tooth surface.…”

mentioning

confidence: 99%

“…The anticaries effect of MFP derives from a complicated set of concomitant interactions at the tooth surface. This probably includes adsorption onto the tooth surface initially, although there is no simple correlation between total fluoride uptake and caries reduction [Aasenden et al, 1972;Mellberg and Ripa, 1983;Retief et al, 1987], It is useful to deter mine how various parameters can influence the up take of fluorides into dental enamel. Uptake of MFP by hydroxyapatite (FlAp) has been studied previously by a number of investigators under varying condi tions [Ericsson, 1963;Ingram, 1968;Gron etal., 1971;Ingram, 1972;1973;Eanes, 1976;Benton et al, 1980].…”

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confidence: 99%