The Relationship between Dietary Calcium and Age-Related Macular Degeneration

Chen, Yuan‐Yuei; Chen, Ying-Jen

doi:10.3390/nu15030671

Cited by 5 publications

(3 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is also related to retinal vascular diameter and length, which are important in patients with age-related macular degeneration, as this decreases and narrows during the course of the disease [ 416 , 417 ]. Additionally, it has been reported that some eye diseases, such as glaucoma and macular degeneration, are related to the alteration of calcium-dependent mechanisms, because a high concentration of calcium was an important factor inducing fibrosis, which contributed to fibrotic damage in glaucomatous optic neuropathy [ 418 ]. Therefore, it is reasonable to assume that dietary calcium could play an important role in the progression of age-related macular degeneration [ 418 ].…”

Section: The Importance Of Dietary Patterns On Visual Healthmentioning

confidence: 99%

Personalizing Nutrition Strategies: Bridging Research and Public Health

Clemente-Suárez,

Peris-Ramos,

Redondo-Flórez

et al. 2024

JPM

View full text Add to dashboard Cite

In recent years, although life expectancy has increased significantly, non-communicable diseases (NCDs) continue to pose a significant threat to the health of the global population. Therefore, eating habits have been recognized as key modifiable factors that influence people’s health and well-being. For this reason, it is interesting to study dietary patterns, since the human diet is a complex mixture of macronutrients, micronutrients, and bioactive compounds, and can modulate multiple physiological processes, including immune function, the metabolism, and inflammation. To ensure that the data we acquired were current and relevant, we searched primary and secondary sources, including scientific journals, bibliographic indexes, and databases in the last 15 years with the most relevant articles. After this search, we observed that all the recent research on NCDs suggests that diet is a critical factor in shaping an individual’s health outcomes. Thus, cardiovascular, metabolic, mental, dental, and visual health depends largely on the intake, habits and patterns, and nutritional behaviors. A diet high in processed and refined foods, added sugars, and saturated fats can increase the risk of developing chronic diseases. On the other hand, a diet rich in whole, nutrient-dense foods, such as vegetables, fruits, nuts, legumes, and a high adherence to Mediterranean diet can improve health’s people.

show abstract

Section: The Importance Of Dietary Patterns On Visual Healthmentioning

confidence: 99%

Personalizing Nutrition Strategies: Bridging Research and Public Health

Clemente-Suárez,

Peris-Ramos,

Redondo-Flórez

et al. 2024

JPM

View full text Add to dashboard Cite

show abstract

“…8 Previous studies on GERD have discussed some prevalence and risk factors globally and locally. 2,4,5,[9][10][11] However, the studies lack some profiles on the inpatients and outpatients of clinically diagnosed GERD patients, particularly in West Sumatra. Therefore, this study aimed to describe the characteristics of GERD patients in Dr. M. Djamil Padang Central General Hospital as the tertiary referral hospital.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of Gastroesophageal Reflux Disease (GERD) Patients at RSUP Dr. M. Djamil Padang Period 2018-2021

Setiawan,

Fasrini,

Amir

et al. 2024

InaJGHE

View full text Add to dashboard Cite

Background: Gastroesophageal reflux disease (GERD), a common digestive problem, is increasing and affecting the individual’s quality of life. This study aimed to describe the characteristics of GERD patients at Dr. M. Djamil Central General Hospital.Method: This cross-sectional study used data from patients' medical records that involved 111 GERD patients, excluding chronic disease and pregnancy. The analysis used univariate analysis and performed the data in cross-tables.Results: The results indicated that demographically, nearly all of the samples fall within the range of productive age (94.59%), with a higher proportion of the female gender (54.05%), the majority having a middle education level (72.08%), being housewives (27.92%), and residing in Padang City (35.13%). Most of the main symptoms were heartburn (62.16%), followed by vomiting, nausea, and dysphagia (4.50%, 2.70%, and 1.80%). More patients received outpatient treatment with two visits (18.02%). Clinically, based on the BMI, the obese classification was higher (43.25%). The levels of triglycerides and total cholesterol in the blood of GERD patients were more in the normal category (60.60% and 61.80%), while the levels of HDL and LDL in the blood of GERD patients were in the abnormal category, with lower HDL (97.80%), and a higher LDL (72.70%).Conclusion: The majority of GERD patients were in the productive age group, female, middle level of education, housewives, and resided in Padang. Clinical characteristics of GERD patients included most were categorized as obese according to their BMI, main symptom heartburn, and treated as an outpatient. Triglyceride and total cholesterol were primarily normal; blood HDL and LDL were abnormal.

show abstract

“…Consequently, an ever-growing cadre of researchers has begun to discern the nexus between diet and ocular physiology and pathology. Prior investigations have underscored the a rmative impact of nutrient intake, including lutein, proteins, and carotenoids, on ocular maladies such as diabetic retinopathy, age-related macular degeneration, and retinopathy of prematurity [14,15]. Simultaneously, an injudicious dietary regimen is also deemed a pivotal precipitant of several ocular ailments.…”

Section: Introductionmentioning

confidence: 99%

Dietary composition plays a crucial role in the development of myopia through the inflammatory pathway: a Mendelian randomization study

Deng

Qin

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Myopia is a major cause of global visual impairment, posing significant public health concerns, impacting daily lives, and leading to severe complications. Dietary factors may influence myopia development, while inflammation plays a role in various diseases and may contribute to myopia occurrence. This study aimed to investigate the impact of carbohydrate, protein, fat, and sugar intake on myopia using MR analysis. Additionally, we explored inflammation's potential role as a mediator. By elucidating partial mechanisms of myopia and providing innovative prevention strategies, we aim to alleviate the global burden of myopia on public health. Methods: We performed mediation MR analyses using large-scale GWAS data from the SSGAC database for four dietary components (carbohydrates, fats, proteins, sugars) of European ancestry, as well as inflammation-related factors (adiponectin, C-reactive protein, tumor necrosis factors, interleukins, nuclear factor-kappa B subunit gamma inhibitor) of European ancestry from the IEU database, and large-scale GWAS data for myopia of European ancestry from the IEU database. Additionally, we conducted bidirectional two-sample MR analyses among selected inflammation-related factors to explore their interrelationships. The inverse-variance weighted method was used as the primary analysis approach, supplemented by comprehensive sensitivity analyses. Results: Inverse-variance weighted models showed positive associations between protein and fat intake and myopia risk. Carbohydrate and sugar intake had no significant association with myopia risk. Adiponectin was negatively correlated, while C-reactive protein and interleukin-18 were positively associated with myopia risk. No significant correlations were found for other inflammation-related factors. Protein intake correlated positively with tumor necrosis factor-alpha and negatively with tumor necrosis factor-beta. Fat intake correlated positively with adiponectin and tumor necrosis factor-alpha, and negatively with interleukin-27. No significant associations were observed for protein and fat intake with other inflammation-related factors. No significant associations were found between pairs of inflammation-related factors. Conclusions: Our findings suggest that a high-fat and high-protein diet may increase myopia risk. Inflammation likely contributes to myopia, but underlying mechanisms are unclear. Excessive protein and fat intake may worsen inflammation. These findings emphasize the importance of dietary modifications and inflammation control for myopia prevention. Further research is needed to understand specific mechanisms and develop targeted dietary interventions.

show abstract

The Relationship between Dietary Calcium and Age-Related Macular Degeneration

Cited by 5 publications

References 74 publications

Personalizing Nutrition Strategies: Bridging Research and Public Health

Personalizing Nutrition Strategies: Bridging Research and Public Health

Characteristics of Gastroesophageal Reflux Disease (GERD) Patients at RSUP Dr. M. Djamil Padang Period 2018-2021

Dietary composition plays a crucial role in the development of myopia through the inflammatory pathway: a Mendelian randomization study

Contact Info

Product

Resources

About