This study examined the interaction between organizational culture, organizational citizenship behaviors and job satisfaction. While organizational culture plays an important role in affecting performance, other variables mediate and moderate the relationship. This study was based on a sample of 127 Egyptian participants undertaking an MBA course. Results showed positive significant correlations between four types of organizational culture, job satisfaction and citizenship behavior individually. Job satisfaction mediated the relationship between culture and citizenship behavior. However, the mediation effect was weak. Further discussion, implications and research limitations are provided.