Abstract-Objectives:To determine whether, hand's temperature, wearing glove, body mass index (BMI), and hand anthropometry have an influence on the hand grip strength in healthy male students. Methods: This cross-sectional descriptive study on eighteen healthy male volunteers, the mean of age (Standard Deviation) is 29.78 (2.9) years. Their ages and anthropometric characteristics including BMI, hand length, hand width, hand depth, hand palm and wrist circumference were measured. The hand was exposed to different bath temperatures ( ) and hand grip strength was measured using a Jamar hydraulic hand dynamometer with and without wearing chemical protection gloves. The data were analyzed using Shapiro-Wilk parametric test, Pearson correlation coefficient, and ANOVA. Results: ANOVA results show a significant effect of wearing a glove on hand grip strength, but there is no significant effect of changing skin temperature on hand grip strength. With respect to anthropometry measurements, a Pearson correlation coefficient matrix demonstrated an only significant correlation between the hand grip and hand width, but the other factors haven't any correlation with hand grip strength. Conclusion: Only wearing glove has an influence on the hand grip strength. Hand width has a significant impact on hand grip strength, but the other factors have no significant impact on hand grip strength in this study.