The Relationship between Hypoalbuminemia and Intradialytic Hypotension in Haemodialysis Patients

Abstract

Objective: To evaluate the relationship between Serum albumin and Intradialytic Hypotension (IDH). Background: Hypoalbuminemia and Intradialytic Hypotension (IDH) is a common complication during HD session. Hypotension is a risk factor for mortality and morbidity in HD patients. Patients and methods: We conducted a cross-sectional study on 50 patients with ESRD who received regular hemodialysis session 3 times weekly for more than 3 months (from April to July 2017) at Ashmoun General Hospital. They have been divided into two groups; Group 1: Patients of this group developed recurrent attacks of IDH and Group 2: Patients of this group did not develop IDH. Data collected from each patient included: (I) Demographic features, clinical features (blood pressure changes during session, ultrafiltration rate, intradialytic weight gain (IDWG), duration of dialysis, cause of ESRD, surface area of dialyzer and blood flow of the machine), (II) Blood chemistry (creatinine, urea, hemoglobin, hematocrit value, albumin, triglycerides, cholesterol, AST, ALT, Na*,K*and KT/V), (III) Echocardiographic assessment of left ventricular geometry and (IV) IVC guided ultrasonography. Result: Serum albumin level among group I ranged between 2.4-4.7 mg/dl with mean ± SD 3.1 ± 0.53 mg/dl, while in group II serum albumin level ranged between 2.6-4.6 mg/dl with mean ± SD 3.6 ± 0.48 mg/dl with p-value 0.002 and there were a high significant difference between both groups. Conclusion: We concluded that serum albumin is a parameter which is associated with intradialytic hypotension and found that beside measurement of IVCC and IVCD are easy and good markers for prediction of intradialytic hypotension.