2019
DOI: 10.1097/ijg.0000000000001164
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The Relationship Between Long-term Use of Intranasal Corticosteroid and Intraocular Pressure

Abstract: Purpose: The purpose of this study was to investigate the association between long-term intranasal steroid use and intraocular pressure (IOP) elevation. Patients and Methods: In total, 100 eyes from 50 patients on long-term intranasal steroids (>2 y) for allergic rhinitis and 90 eyes from 45 controls were included in this study. Patients on other forms of steroids and risk factors for glaucoma were excluded. IOP was measured and nonmydriatic stereosc… Show more

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Cited by 11 publications
(8 citation statements)
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“…By far, the most common treatment method is intranasal corticosteroids [ 8 ]. The long-term use of steroids, however, is associated with adverse effects, including intraocular pressure elevation [ 9 ], nasal dryness, and disruptions to taste and smell [ 10 ]. There is a need, therefore, for new, safer, and more economical alternative therapeutic agents to treat allergic disorders.…”
Section: Introductionmentioning
confidence: 99%
“…By far, the most common treatment method is intranasal corticosteroids [ 8 ]. The long-term use of steroids, however, is associated with adverse effects, including intraocular pressure elevation [ 9 ], nasal dryness, and disruptions to taste and smell [ 10 ]. There is a need, therefore, for new, safer, and more economical alternative therapeutic agents to treat allergic disorders.…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, the long-term impact of intranasal steroids on IOP was studied by Mohd Zain et al [19]. The results showed that the mean IOP was slightly higher in the intranasal test group (15.24 ± 2.31 mmHg) than in the control group (13.91 ± 1.86 mm Hg).…”
Section: Discussionmentioning
confidence: 99%
“…Although an increase in intraocular pressure compared with placebo has been detected, the levels usually remain within normal range and glaucomatous optic disc changes have not been noted. 98 A recent systematic review and meta-analysis looked at more than 424 studies, including 10 randomized controlled trials, to help answer these questions. 99 The authors found that the absolute increased incidence of elevated IOP in patients using INS vs placebo was 0.8% but there were no cases of glaucoma at 12 months.…”
Section: Topical Corticosteroidsmentioning
confidence: 99%
“…73 When using intranasal corticosteroids on a prolonged basis, especially in high doses, an annual eye examination and IOP measurement should be considered. 98…”
Section: Topical Corticosteroidsmentioning
confidence: 99%
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