The Relationship between Migraine Pain and Other Associated Symptoms

Abstract

This study explores the relationship of the pain of the migraine headache and the associated features of migraine. Migraineurs (n=1025) (ICHD-2, 1.1-1.2 and 1.5.1) were evaluated retrospectively using a detailed database (daily unremitting excluded). Variables studied included headache intensity and duration, associated symptoms and pain characteristics. Non-parametric correlations were used to evaluate relationships among variables. Headache intensity correlated with nausea, vomiting, photophobia, phonophobia, dizziness (all P=0.000), running of the nose/tearing of the eyes (P=0.007), and osmophobia (P=0.044), but not with diarrhoea or taste abnormality. Headache duration correlated only with osmophobia (P=0.002) and taste abnormality (P=0.005). Throbbing, pressure and stabbing pain correlated with most of the associated symptoms. Aching correlated only with taste abnormality. This correlational study demonstrates that migraine pain is clearly related to nausea, but is also correlated with other associated migraine symptoms. Taste abnormality and osmophobia are better correlated with headache duration rather than headache intensity.

Topographic Analysis of Electroencephalographic Changes during Photic Driving Responses in Patients with Migraine

“…Photic hypersensitivity is reportedly seen in 76.4 to 93.9% of all patients with migraine [6,7]. Photic hypersensitivity was seen in 78.6% of our study population comprising outpatients with headache at our university hospital, and this result was consistent with those of previous reports.…”

Evaluation of Electroencephalogram Using Exact Low-Resolution Electromagnetic Tomography During Photic Driving Response in Patients with Migraine

“…Photic hypersensitivity was observed in 74% of migraine patients in our study, which was slightly lower compared to previous studies that reported a photic hypersensitivity prevalence of 76.4–93.9% in patients with migraine [7, 8]. The photic driving response, which is a concurrent reaction relevant to vision, was first reported in 1934 [9].…”

Sumatriptan Iontophoretic Transdermal System for the Acute Treatment of Migraine

“…Gastro intestinal (GI) symptoms, such as nausea and vomiting, are very important clinical features and extremely common in migraine, with an estimated presence during attacks in two-thirds and a third of migraineurs, respectively [2]. In addition, the presence of nausea and vomiting has been shown to be related to the intensity of the migraine headache [5].…”