The relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diastolic heart failure in patients with COVID-19

Ziaie, Naghmeh; Ezoji, Khadijeh; Ziaei, Seyedeh Golnaz; Chehrazi, Mohammad; Maleh, Parviz Amri; Pourkia, Roghayeh; Seyfi, Shahram

doi:10.1007/s10554-021-02513-8

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…These findings revealed that grade 2 or greater diastolic dysfunction in COVID‐19 individuals was related with increased NT‐proBNP levels. [ 65 ]…”

Section: Brain and Heart Communication In Covid‐19 Patientsmentioning

confidence: 99%

A critical review on brain and heart axis response in COVID‐19 patients: Molecular mechanisms, mediators, biomarkers, and therapeutics

Abha Mishra,

Podili,

Pathlavath

et al. 2023

J Biochem & Molecular Tox

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Since the outbreak of highly virulent coronaviruses, significant interest was assessed to the brain and heart axis (BHA) in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐affected patients. The majority of clinical reports accounted for unusual symptoms associated with SARS‐CoV‐2 infections which are of the neurological type, such as headache, nausea, dysgeusia, anosmia, and cerebral infarction. The SARS‐CoV‐2 enters the cells through the angiotensin‐converting enzyme (ACE‐2) receptor. Patients with prior cardiovascular disease (CVD) have a higher risk of COVID‐19 infection and it has related to various cardiovascular (CV) complications. Infected patients with pre‐existing CVDs are also particularly exposed to critical health outcomes. Overall, COVID‐19 affected patients admitted to intensive care units (ICU) and exposed to stressful environmental constraints, featured with a cluster of neurological and CV complications. In this review, we summarized the main contributions in the literature on how SARS‐CoV‐2 could interfere with the BHA and its role in affecting multiorgan disorders. Specifically, the central nervous system involvement, mainly in relation to CV alterations in COVID‐19‐affected patients, is considered. This review also emphasizes the biomarkers and therapy options for COVID‐19 patients presenting with CV problems.

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“…These findings revealed that grade 2 or greater diastolic dysfunction in COVID‐19 individuals was related with increased NT‐proBNP levels. [ 65 ]…”

Section: Brain and Heart Communication In Covid‐19 Patientsmentioning

confidence: 99%

A critical review on brain and heart axis response in COVID‐19 patients: Molecular mechanisms, mediators, biomarkers, and therapeutics

Abha Mishra,

Podili,

Pathlavath

et al. 2023

J Biochem & Molecular Tox

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Prediction of Diastolic Dysfunction in Patients With Cardiovascular Diseases and Type 2 Diabetes With Respect to Covid-19 in Anamnesis Using Artificial Intelligence

Alimova,

Ikramov,

Trigulova

et al. 2023

2023 the 7th International Conference on Medical and Health Informatics (ICMHI)

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ASSOCIATIONS BETWEEN STRUCTURAL AND FUNCTIONAL STATUS OF MYOCARDIUM AND SERUM LEVELS OF NT-proBNP AND ST2 IN PATIENTS WITH COMBINED CARDIAC PATHOLOGY

Іванов

Zakrevska

2023

Act. Probl. of the Modern Med.

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Damage to the heart under essential hypertension manifests a combination of changes in the left ventricle, left atrium, and coronary arteries resulted from a chronic elevation in blood pressure. Hypertension increases the load on the heart, causing structural and functional changes in the myocardium. Associations between clinical, laboratory and instrumental indicators and the levels of various biomarkers, which characterize the specificity and severity of systemic processes occurring in the cardiovascular system and can also be used for predicting the prognosis of diseases, are of undoubted practical interest. The aim of this study was to research the associations between the structural and functional state of the myocardium and the levels of serum NT-proBNP and ST2 in hypertensive patients with / without chronic coronary disease. Materials and methods. 118 patients with stage II hypertension with / without chronic coronary disease were included in the study. For all patients, both the main indicators of the structural and functional state of the myocardium according to echocardiography and serum levels of NT-proBNP and ST2 were additionally measured on the 2-3rd day of hospital stay when optimal therapy was being selected. Results. The obtained data indicate that a relatively low level of NT-proBNP is associated with a significant increase in the size of the right atrium and the right atrial index and the frequency of cases with concentric hypertrophy of the left ventricle compared to intermediate and relatively high levels of the neurohormone. The patients with relatively low neurohormone level demonstrate a significant increase in end-diastolic size and left atrial size compared with only intermediate levels. The results of the analysis of changes in echocardiogram indicators depending on the level of ST2 in plasma demonstrate the complete absence of any reliable changes between the selected groups.

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The relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diastolic heart failure in patients with COVID-19

Cited by 3 publications

References 19 publications

A critical review on brain and heart axis response in COVID‐19 patients: Molecular mechanisms, mediators, biomarkers, and therapeutics

A critical review on brain and heart axis response in COVID‐19 patients: Molecular mechanisms, mediators, biomarkers, and therapeutics

Prediction of Diastolic Dysfunction in Patients With Cardiovascular Diseases and Type 2 Diabetes With Respect to Covid-19 in Anamnesis Using Artificial Intelligence

ASSOCIATIONS BETWEEN STRUCTURAL AND FUNCTIONAL STATUS OF MYOCARDIUM AND SERUM LEVELS OF NT-proBNP AND ST2 IN PATIENTS WITH COMBINED CARDIAC PATHOLOGY

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