2023
DOI: 10.1016/j.jcrc.2023.154359
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The relationship between pain, anxiety and depression in patients with post-intensive care syndrome

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Cited by 6 publications
(5 citation statements)
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“…15 It has been reported that between 44 and 77% of ICU survivors will go on to develop chronic pain within 6 months to 1 year post-ICU discharge. 11,[16][17][18] The evolution from acute (or acute-on-chronic) to chronic pain is mediated by several factors including proinflammatory processes, heightened neuronal membrane excitability, and central sensitization. 15 Risk factors for the development of chronic pain include female sex, ventilator hours, hospital length of stay, sepsis, trauma, elevated C-reactive protein levels, prior use of antidepressant medication, increasing patient's age, hyperinflammation, and prone positioning.…”
Section: Risk Factors For Pics In Brain-injured and Non-brain-injured...mentioning
confidence: 99%
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“…15 It has been reported that between 44 and 77% of ICU survivors will go on to develop chronic pain within 6 months to 1 year post-ICU discharge. 11,[16][17][18] The evolution from acute (or acute-on-chronic) to chronic pain is mediated by several factors including proinflammatory processes, heightened neuronal membrane excitability, and central sensitization. 15 Risk factors for the development of chronic pain include female sex, ventilator hours, hospital length of stay, sepsis, trauma, elevated C-reactive protein levels, prior use of antidepressant medication, increasing patient's age, hyperinflammation, and prone positioning.…”
Section: Risk Factors For Pics In Brain-injured and Non-brain-injured...mentioning
confidence: 99%
“…17,19,20 Increasing evidence has indicated a relationship with chronic pain and the psychological domain symptoms associated with PICS, most specifically anxiety and depression. 16 For patients with neurological injuries, the complexity of pain and pain management becomes increasingly more challenging. Patients with SABI often present with disorders of consciousness, need for mechanical ventilation, and alterations in neurological function including pain processing, aphasia, and dysarthria.…”
Section: Risk Factors For Pics In Brain-injured and Non-brain-injured...mentioning
confidence: 99%
“…PICS is also associated with cognitive deficits, mostly including anxiety, depression, and PTSD [ 11 ]. Survivors of critical illness experience a significant level of physical discomfort, which is linked to a higher likelihood of depression and anxiety in these individuals [ 14 ]. Admission to the ICU is frequently abrupt and poses a significant risk to the patient's life.…”
Section: Reviewmentioning
confidence: 99%
“…Delirium is the predominant consequence associated with cognitive impairment in patients with PICS, according to multiple studies examining risk variables. The negative experiences of ICU patients, including instances of poor patient experience and delirium, significantly contribute to the development of anxiety, sadness, and PTSD [ 14 - 16 , 18 , 19 ]. Ahmad et al further stated that delirium is identified as a separate risk factor that contributes to cognitive impairment after six and 12 months [ 17 ].…”
Section: Reviewmentioning
confidence: 99%
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