The Relationship Between Psychological Symptoms and Ventricular Assist Device Implantation

Weerahandi, Himali; Goldstein, Nathan E.; Gelfman, Laura P.; Jorde, Ulrich P.; Kirkpatrick, James N.; Meyerson, Edith M.; Marble, J.; Naka, Yoshifumi; Pinney, Sean; Slaughter, Mark S.; Bagiella, Emilia; Ascheim, Deborah D.

doi:10.1016/j.jpainsymman.2017.05.002

Cited by 11 publications

(14 citation statements)

References 29 publications

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“…In contrast, the t-score changed to 44 (±6) and 42 (±9), respectively, 48 weeks after implantation. When plotted on a generalized linear mixed (GLM) model, a decrease overtime signifying improvement with P=0.03 and P<0.001 for depression and anxiety, respectively, was observed [ 18 ]. Another study by Shah et al showed improvement in health-related quality of life (HRQOL), depression, and heart failure symptoms seen in LVAD patients as compared to patients on medical management in the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) 4 group [ 19 ].…”

Section: Reviewmentioning

confidence: 99%

“…-Twenty observational studies of which eight were prospective cohort studies, five retrospective cohort studies, six cross-sectional studies, and one qualitative study [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] -One randomized clinical trial [32] -One systematic review (n=1887) [33] -Four literature reviews [7,[34][35][36] -One practice guideline [1].…”

Section: Reviewmentioning

confidence: 99%

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Psychological Spectrum Experienced by Heart Failure Patients After Left Ventricular Assist Device Implantation

Okam

Ahmad

Rana

et al. 2020

Cureus

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Depression and anxiety disorders are prevalent in patients with heart failure. They are associated with adverse effects such as rapid disease progression, poor medication compliance, low quality of life and increased mortality rate. The current literature review aims to provide an overview of the overall rate of depression in patients who receive left ventricular assist device (LVAD) implantation and identify the psychological phases that these individuals experienced peri- and post-LVAD implantation. A PubMed search using regular and Medical Subject Headings (MeSH) keywords identified 239 articles. After applying inclusion/exclusion criteria, removal of duplicate studies, and careful review of articles, 40 studies provided relevant information on our primary end-point. These 40 studies selected include 13 paid articles with abstracts and 27 free full-text articles comprising eight prospective cohort studies, five retrospective cohort studies, six cross-sectional studies, one qualitative study, one randomized clinical trial, one systematic review, four literature reviews, and one practice guide. Our review shows that patients experienced different psychological phases after LVAD implantation. However, as the time from implantation progressed, these patients showed a significant improvement in depression, anxiety, and health-related quality of life.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Psychological Spectrum Experienced by Heart Failure Patients After Left Ventricular Assist Device Implantation

Okam

Ahmad

Rana

et al. 2020

Cureus

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“…Częstość występowania depresji i lęku jest zmienna na różnych etapach leczenia LVAD. Nasila się tuż przed implantacją, ustępuje krótko po niej i ponownie rośnie, jeśli problemy chorego z przystosowaniem się przewyższają umiejętności radzenia sobie [2,33]. U pacjentów ze schyłkową niewydolnością serca objawy depresyjne są najczęściej związane ze stopniem zaawansowania choroby serca, w tym z gorszym funkcjonowaniem fizycznym i gorszym rokowaniem odległym.…”

Section: Okres Pooperacyjnyunclassified

Preparation for implantation of mechanical circulatory support: psychological adjustment and treatment of mental disorders in the pre- and postoperative period

Jaworska,

Pudlo,

Mierzyńska

et al. 2024

Psychiatr Pol

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Leczenie pacjentów z zawansowaną niewydolnością serca poprzez zastosowanie urządzeń wspomagających pracę lewej komory (LVADs – left ventricular assist devices) poprawia jakość życia i długość przeżycia. Poza niezaprzeczalnymi korzyściami związanymi z poprawą wydolności fizycznej na skutek ustąpienia objawów choroby podstawowej, niesie ono ryzyko powikłań w obszarze zdrowia somatycznego i psychicznego pacjenta. Długotrwała niewydolność krążenia, może przyczyniać się do osłabienia mechanizmów adaptacyjnych i w konsekwencji prowadzić do powstania różnego rodzaju zaburzeń emocjonalnych. Pacjenci muszą zmierzyć się z lękiem przed nadchodzącymi fizycznymi, rodzinnymi i społecznymi zmianami, które pociąga za sobą LVAD. Mogą wystąpić u nich zaburzenia nastroju, zaburzenia lękowe czy zaburzenia snu, a we wczesnym okresie pooperacyjnym również zaburzenia świadomości o obrazie majaczenia. Z tego powodu, na każdym etapie leczenia, wskazane jest objęcie chorego interdyscyplinarną opieką medyczną, w tym regularnym monitorowaniem ogólnego stanu zdrowia z uwzględnieniem stanu psychicznego. Artykuł przedstawia czynniki ryzyka sprzyjające wystąpieniu zaburzeń psychicznych u pacjentów z LVAD oraz sposoby farmakologicznego i niefarmakologicznego postępowania w sytuacji identyfikacji tych czynników i rozpoznania zaburzeń.

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“…Elevated rates of depression, anxiety, and decreased QOL have been identified in posttransplant patients and inconsistently in VAD patients [6][7][8]. However, there is limited evidence as to the effect of other mental health disorders (MHDs) and SUDs.…”

Section: Introductionmentioning

confidence: 99%

Mental Health and Substance Use Disorders in Transplant Waitlist, VAD, and Heart Transplant Patients: A TriNetX Database Analysis

Grzyb,

Du,

Mahesh

et al. 2024

Preprint

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Background/ObjectivesMental health and substance use disorders (MHD, SUD) affect cardiac allograft and VAD recipients and impact their quality of life and compliance. Limited research on MHDs and SUDs in transplant and MCS candidates and recipients. This study compares the incidence of MHDs and SUDs in transplant list, VAD, and post-transplant patients with that in heart failure patients. MethodsStudy cohorts were derived from the TriNetX using ICD-10 codes. Differences in incidence were examined using the log-rank test. Adults with mental health disorders before the window of time were excluded. Propensity score matching was performed using TriNetX to balance demographic and medical comorbidities. Statistical significance was set at p<0.05. All comparisons were made between propensity-matched cohorts. ResultsTransplant waitlist patients showed a statistically significant increase in the incidence of anxiety, panic disorder, adjustment disorder, depression, mood disorder, alcohol use disorder, and eating disorder. Post-transplant patients showed a statistically significant increase in the incidence of depression and opioid use compared to the heart failure population. VAD patients showed a statistically significant increase in the incidence of depression and a statistically significant decrease in panic disorder and anxiety. ConclusionsThe results pave the pathway for further investigations on prevention and coping strategies because deterioration of mental health will significantly impact compliance with medications as well as patient survival and quality of life. The use of opioids for pain management in the early postoperative period should be further investigated to assess its impact on long-term substance use and addiction. .

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The Relationship Between Psychological Symptoms and Ventricular Assist Device Implantation

Cited by 11 publications

References 29 publications

Psychological Spectrum Experienced by Heart Failure Patients After Left Ventricular Assist Device Implantation

Psychological Spectrum Experienced by Heart Failure Patients After Left Ventricular Assist Device Implantation

Preparation for implantation of mechanical circulatory support: psychological adjustment and treatment of mental disorders in the pre- and postoperative period

Mental Health and Substance Use Disorders in Transplant Waitlist, VAD, and Heart Transplant Patients: A TriNetX Database Analysis

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