“…This underscores the need to consider the patient's subjective experience of his or her well-being and functional status in all phases of illness, and not only in advanced or terminal cancer, where poor well-being is, in fact, associated with hopelessness, depression, suicidal ideation, and poor quality of life. 14,39 Interestingly, no other psychosocial variables, even previous psychiatric episodes, stressful events in the last year, or spiritual beliefs, were related to hopelessness. Likewise, medical variables, such as stage and site of cancer or type of treatment, did not appear to influence hopelessness, although breast cancer patients reported lower scores than patients with other types of cancer.…”