The relationship between red blood cell distribution width and blood pressure in patients with type 2 diabetes mellitus in Lagos, Nigeria

Dada, Olusola; Uche, Ebele; Akinbami, Akinsegun; Majeed, Odesanya; John‐Olabode, Sarah; Adediran, Adewumi; Oshinaike, Olajumoke; Ogbera, Anthonia O; Okunoye, Olaitan; Arogundade, Olanrewaju; Kingsley, Aile; Ekwere, Timothy Amos

doi:10.2147/jbm.s67989

Cited by 16 publications

(11 citation statements)

References 29 publications

(33 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 22 , 36 – 39 This is due to the fact that high RDW indicates impairment of erythropoiesis, reflecting chronic inflammation and increased levels of oxidative stress, both of which are significant signs of T2DM that result in the RBC size variation. 40 In contrary, studies in Turkey and Nigeria reported that significant difference was not observed between cases and controls in RDW level. 39 , 40 Differences in study design and ethnic and cultural differences across the study populations may account for the variability of RDW across studies.…”

Section: Discussionmentioning

confidence: 93%

See 1 more Smart Citation

Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia

Biadgo¹,

Melku²,

Abebe³

et al. 2016

DMSO

View full text Add to dashboard Cite

BackgroundDiabetes mellitus is (DM) a global public health problem and a complex disease characterized by chronic hyperglycemia that leads to long-term macrovascular and microvascular complications. Recent studies have reported the role of hematological indices in contributing to the vascular injury in diabetic patients. Thus, the aim of this study was to determine hematological indices and their correlation with fasting blood glucose level and anthropometric measurement in type 2 DM patients in comparison with healthy controls.MethodsA comparative cross-sectional study was conducted at the chronic illness clinic of Gondar University Hospital from February to April 2015. A total of 296 participants (148 cases and 148 healthy controls) were selected using systematic random sampling technique. Data were collected using a pretested structured questionnaire. Fasting blood glucose levels and hematological indices were determined by using Bio Systems A25 and Sysmex-KX 21N analyzers, respectively. Independent sample t-test, Mann–Whitney U-test, and correlation statistics were used. A P-value <0.05 was considered as statistically significant.ResultThere was significant difference in red blood cell distribution width (47.3±2.6 fL vs 45.2±3 fL) between diabetic patients and controls. Total white blood cells in 103/µL (6.59±1.42 vs 5.56±1.38), absolute lymphocyte count in 103/µL (2.60±0.70 vs 2.04±0.63), and absolute neutrophil count in 103/µL (3.57±1.46 vs 3.11±1.04) increased significantly in diabetic patients compared with controls, respectively. Among platelet indices, mean platelet volume (10.4±1.1 fL vs 9.9±1.1 fL) and platelet distribution width (14.5±2.1 fL vs 13.4 ±2.1 fL) were found to be significantly increased in the diabetic patients (P<0.05). Anthropometric measurements significantly correlated with white blood cell and platelet indices.ConclusionThe study showed statistically significant difference in some hematological parameters of diabetic patients compared to controls. Thus, hematological indices could be useful indicators of vascular complication and glycemic control in type 2 DM patients.

show abstract

Section: Discussionmentioning

confidence: 93%

“… 40 In contrary, studies in Turkey and Nigeria reported that significant difference was not observed between cases and controls in RDW level. 39 , 40 Differences in study design and ethnic and cultural differences across the study populations may account for the variability of RDW across studies.…”

Section: Discussionmentioning

confidence: 93%

Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia

Biadgo¹,

Melku²,

Abebe³

et al. 2016

DMSO

View full text Add to dashboard Cite

show abstract

“…There is a defect in insulin effect, secretion or both [1,2]. As obesity and sedentary life style is common in the society, DM type 2 frequency is increasing [3].…”

Section: Introductionmentioning

confidence: 99%

Correlation between red blood cell distrubition width and glycated hemoglobin in diabetic and nondiabetic patients

Dilara¹,

Hülya²,

Kilinc³

et al. 2016

Russ Open Med J

View full text Add to dashboard Cite

Aim -Our aim in this study is evaluating the red blood cell distrubition width (RDW) and glycated hemoglobin (HbA1C) relation in nondiabetic and diabetic people who applied to our hospital and showing the usability in disease follow-up. Material and Methods -Main data of this research is the data of patients (diabetic and nondiabetic) who applied to internal diseases polyclinic between July 1, 2013 and November 31, 2014 and whose RDW, HbA1C, white blood cell, hemoglobin, and hematocrit were controlled. 82 diabetic and 32 nondiabetic patients were included in this study. Results -No statistically significant difference was observed between the diabetic and nondiabetic groups in age, male and female distribution and RDW. No statistically significant correlation was observed between RDW and age and HbA1C in order in the nondiabetic group. While a correlation which is statistically significant and in the same direction was determine between age and RDW among the diabetic group, a statistically significant correlation was not between HbA1C and RDW. Among all cases a correlation which is statistically meaningful and in the same direction was detected between age and RDW. But a statistically significant correlation was not found between HbA1C and RDW among all cases. Conclusion -According to the available results, no statistically significant correlation was determined between HbA1C and RDW in the nondiabetic patients, diabetic group or in total. But in order to provide more clearance, we believe that studies with more patients would be useful.

show abstract

“…There are two types of DM; 1) type I diabetes that is commonly observed in children and adults and is related to insulin defects, and 2) type II diabetes that occurs in adults and accounts for more than 90% of all cases of diabetes in the world. The risk factors for type 3 diabetes include low activity, obesity, and aging (6). Nowadays, type 2 diabetes is one of the most common and complicated problems of the community.…”

Section: Introductionmentioning

confidence: 99%

Red cell distribution width as a prognostic marker in diabetes; a pilot cross-sectional study

Shirali¹,

Bahadoram²,

Nourbakhsh³

et al. 2018

J Nephropharmacol

View full text Add to dashboard Cite

show abstract

The relationship between red blood cell distribution width and blood pressure in patients with type 2 diabetes mellitus in Lagos, Nigeria

Cited by 16 publications

References 29 publications

Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia

Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia

Correlation between red blood cell distrubition width and glycated hemoglobin in diabetic and nondiabetic patients

Red cell distribution width as a prognostic marker in diabetes; a pilot cross-sectional study

Contact Info

Product

Resources

About