The relationship between severity of coronary artery disease and mean platelet volume

Varastehravan, Hamidreza; Naghedi, Aryan; Nough, H; Pourmirafzali, Hamideh

doi:10.12710/cardiometry.2019.14.5763

Cited by 2 publications

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“…Measurements of mean platelet volume (MPV) and Platelet distribution width (PDW), indicating the width and depth of the platelet distribution, are useful indicators of platelet function. 6 Leukocytes, also known as white blood cells, serve as inflammatory markers and play a significant role in the processes of atherogenesis and thrombosis. An easily accessible inflammatory biomarker, the neutrophil-lymphocyte ratio (NLR), is commonly used for risk stratification in individuals with cardiovascular disease.…”

Section: Introductionmentioning

confidence: 99%

Correlation Between Platelet Index, Neutrophil-Lymphocyte Ratio, and Mean Platelet-Volume Lymphocyte Ratio with Lesion in Chronic Coronary Syndrome Based on SYNTAX Score

Fathurohim,

Tri Tjahjono,

Zulhaidah Arthamin

et al. 2024

HSJ

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Background: Platelet aggregation and inflammation have been associated with atherosclerosis, and inflammatory parameters such as mean platelet volume (MPV), platelet distribution width (PDW), neutrophil-lymphocyte ratio (NLR), and mean platelet-lymphocyte volume ratio (MPLVR) are often used. However, the relationship between these inflammatory parameters and the SYNTAX Score in CAD remains uncertain. Objective: The purpose of this study was to investigate the relationship between angiographic SYNTAX score, NLR, and platelet parameters (MPV, PLR, MPLVR). Material and Methods: We conducted a study involving patients undergoing elective coronary angiography from January 2023 to June 2023 at Dr. Saiful Anwar General Hospital, who were 18 years of age or older and had CAD. All participants willingly agreed to be part of the study. We collected complete routine blood counts and performed blood biochemistry assessments 24 hours before the coronary angiography procedure. Pearson's correlation was used to examine the relationship between the variables. Result: A total of 366 individuals meeting the study's inclusion criteria were included. MPV, PLR, MPLVR, NLR, and PDW showed weak to negligible correlations with the SYNTAX Score, displaying correlation coefficients of 0.260, 0.190, 0.320, 0.470, and 0.290, respectively, all with p-values <0.001. Conclusion: This study in individuals with coronary artery disease revealed a limited to negligible correlation between the SYNTAX Score and inflammatory parameters including MPV, PLR, MPLVR, NLR, and PDW.

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Section: Introductionmentioning

confidence: 99%

Correlation Between Platelet Index, Neutrophil-Lymphocyte Ratio, and Mean Platelet-Volume Lymphocyte Ratio with Lesion in Chronic Coronary Syndrome Based on SYNTAX Score

Fathurohim,

Tri Tjahjono,

Zulhaidah Arthamin

et al. 2024

HSJ

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“…En la mayoría de los pacientes existen otros factores de riesgo 3 entre los que destacan el hábito tabáquico, la obesidad abdominal, la hipertensión arterial (HTA), diabetes mellitus (DM), dislipidemia, factores psicosociales y consumo de alcohol 4 . La formación de trombos seguida por la formación de placa aterosclerótica es el factor principal en la patogénesis de la enfermedad coronarias y las plaquetas desempeñan un papel importante 5 . Las plaquetas son células redondas y similares a discos, cuyo recuento normal oscila entre 150000 a 400000 por ml de sangre.…”

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Relación entre el volumen plaquetario medio y la gravedad de la enfermedad arterial coronaria

et al. 2019

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The relationship between severity of coronary artery disease and mean platelet volume

Cited by 2 publications

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Correlation Between Platelet Index, Neutrophil-Lymphocyte Ratio, and Mean Platelet-Volume Lymphocyte Ratio with Lesion in Chronic Coronary Syndrome Based on SYNTAX Score

Correlation Between Platelet Index, Neutrophil-Lymphocyte Ratio, and Mean Platelet-Volume Lymphocyte Ratio with Lesion in Chronic Coronary Syndrome Based on SYNTAX Score

Relación entre el volumen plaquetario medio y la gravedad de la enfermedad arterial coronaria

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