The Relationship of Attitudinal Beliefs to Negative Symptoms, Neurocognition, and Daily Functioning in Recent-Onset Schizophrenia

Ventura, Joseph; Subotnik, Kenneth L.; Ered, Arielle; Gretchen‐Doorly, Denise; Hellemann, Gerhard; Vaskinn, Anja; Nuechterlein, Keith H.

doi:10.1093/schbul/sbu002

Cited by 70 publications

(81 citation statements)

References 50 publications

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“…Consistent with previous studies in those with schizophrenia [13][14][15][16] and those at ultra high risk for psychosis [12], increased defeatist performance beliefs were significantly associated with greater negative schizotypy traits. Importantly, and in line with the aforementioned studies, the relationship between defeatist performance beliefs and negative schizotypy traits remained significant when controlling for both depressive symptoms and positive schizotypy traits.…”

Section: Discussionsupporting

confidence: 88%

“…To date, defeatist performance beliefs -a specific subtype of defeatist beliefs that focuses on overgeneralized negative beliefs about one's ability to successfully perform tasks-have received the most empirical support. Indeed, individuals with schizophrenia have been found to report increased defeatist performance beliefs compared to healthy controls [13][14][15]. Cross-sectional studies have also found that increased defeatist performance beliefs are associated with elevated overall and domain-specific cognitive impairments [13,16] including, for example, deficits in working memory and verbal learning [17].…”

Section: Defeatist Beliefs In Schizotypymentioning

confidence: 99%

“…Defeatist performance beliefs have been assessed in inpatients and outpatients with schizophrenia [13,16], older adults with schizophrenia [19], individuals with deficit syndrome schizophrenia [20], those with recent on-set schizophrenia [15], and veterans with schizophrenia [14]. Despite considerable research in schizophrenia samples, there is a dearth of research investigating defeatist performance beliefs in individuals with schizotypy.…”

Section: Defeatist Beliefs In Schizotypymentioning

confidence: 99%

See 2 more Smart Citations

Additional support for the cognitive model of schizophrenia: evidence of elevated defeatist beliefs in schizotypy

Luther

Salyers

Firmin

et al. 2016

Comprehensive Psychiatry

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Section: Discussionsupporting

confidence: 88%

Section: Defeatist Beliefs In Schizotypymentioning

confidence: 99%

Section: Defeatist Beliefs In Schizotypymentioning

confidence: 99%

See 1 more Smart Citation

Additional support for the cognitive model of schizophrenia: evidence of elevated defeatist beliefs in schizotypy

Luther

Salyers

Firmin

et al. 2016

Comprehensive Psychiatry

View full text Add to dashboard Cite

“…Studies supporting the theory by Cohen et al in regard to schizophrenia have used a self-report measure (Cohen et al, 2012), a clinician rating scale (Chang et al, 2014), or a computerized acoustic analysis (Cohen et al, 2013) to assess symptoms of diminished expression. Recent studies have assessed diminished expression together with apathy in clinical rating scales, reporting mixed results regarding their link to neurocognitive deficits (Galderisi et al, 2014;Gur et al, 2015;Kring et al, 2013;Ventura et al, 2014). Critically, none of these studies investigated the independent relationship of the two negative symptom dimensions with cognitive function.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, studies have investigated correlates of neurocognitive deficits with clinical ratings scales that allow the assessment of both negative symptom dimensions. Ventura et al (2014) used the Scale for Assessment of Negative Symptoms (SANS; Andreasen, 1982) and reported that both dimensions correlated with neurocognitive deficits. Kring et al (2013) and Gur et al (2015) reported no significant correlations using the Clinical Assessment Interview for Negative Symptoms (CAINS; Kring et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

The association of neurocognitive impairment with diminished expression and apathy in schizophrenia

Hartmann-Riemer

Hager

Kirschner

et al. 2015

Schizophrenia Research

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Negative symptoms can be grouped into the two dimensions of diminished expression and apathy, which have been shown to be dissociable regarding external validators, such as functional outcome. Here, we investigated whether these two dimensions differentially relate to neurocognitive impairment in schizophrenia. 47 patients with schizophrenia or schizoaffective disorder and 33 healthy control participants were subjected to a neurocognitive test battery assessing multiple cognitive domains (processing speed, working memory, verbal fluency, verbal learning and memory, mental planning), which are integrated into a composite cognition score. Negative symptoms in patients were assessed using the Brief Negative Symptom Scale. We found that diminished expression significantly related to neurocognitive impairment, while severity of apathy symptoms was not directly associated with neurocognition. Other assessed clinical variables include chlorpromazine equivalents, positive symptoms, and depressive symptoms and did not influence the results. Our results are in line with a cognitive resource limitation model of diminished expression in schizophrenia and indicate that cognitive remediation therapy might be helpful to ameliorate expressive deficits.

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The clinical characterization of the patient with primary psychosis aimed at personalization of management

et al. 2021

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The current management of patients with primary psychosis worldwide is often remarkably stereotyped. In almost all cases an antipsychotic medication is prescribed, with second‐generation antipsychotics usually preferred to first‐generation ones. Cognitive behavioral therapy is rarely used in the vast majority of countries, although there is evidence to support its efficacy. Psychosocial interventions are often provided, especially in chronic cases, but those applied are frequently not validated by research. Evidence‐based family interventions and supported employment programs are seldom implemented in ordinary practice. Although the notion that patients with primary psychosis are at increased risk for cardiovascular diseases and diabetes mellitus is widely shared, it is not frequent that appropriate measures be implemented to address this problem. The view that the management of the patient with primary psychosis should be personalized is endorsed by the vast majority of clinicians, but this personalization is lacking or inadequate in most clinical contexts. Although many mental health services would declare themselves “recovery‐oriented”, it is not common that a focus on empowerment, identity, meaning and resilience is ensured in ordinary practice. The present paper aims to address this situation. It describes systematically the salient domains that should be considered in the characterization of the individual patient with primary psychosis aimed at personalization of management. These include positive and negative symptom dimensions, other psychopathological components, onset and course, neurocognition and social cognition, neurodevelopmental indicators; social functioning, quality of life and unmet needs; clinical staging, antecedent and concomitant psychiatric conditions, physical comorbidities, family history, history of obstetric complications, early and recent environmental exposures, protective factors and resilience, and internalized stigma. For each domain, simple assessment instruments are identified that could be considered for use in clinical practice and included in standardized decision tools. A management of primary psychosis is encouraged which takes into account all the available treatment modalities whose efficacy is supported by research evidence, selects and modulates them in the individual patient on the basis of the clinical characterization, addresses the patient’s needs in terms of employment, housing, self‐care, social relationships and education, and offers a focus on identity, meaning and resilience.

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The Relationship of Attitudinal Beliefs to Negative Symptoms, Neurocognition, and Daily Functioning in Recent-Onset Schizophrenia

Cited by 70 publications

References 50 publications

Additional support for the cognitive model of schizophrenia: evidence of elevated defeatist beliefs in schizotypy

Additional support for the cognitive model of schizophrenia: evidence of elevated defeatist beliefs in schizotypy

The association of neurocognitive impairment with diminished expression and apathy in schizophrenia

The clinical characterization of the patient with primary psychosis aimed at personalization of management

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