This chapter explores the integration of disciplinary literacy across learning stations in PreK through 3rd Grade classrooms to facilitate culturally and linguistically responsive learning. Through a synthesis of research and the professional experience of the authors, the chapter offers a conceptual framework and pedagogical support for literacy practices that are culturally and linguistically responsive to each child's emerging and developing literacy. Additionally, this chapter describes the components of an interdisciplinary approach to facilitating literacy learning at the prekindergarten through third grade level that ensures a culturally and linguistically responsive curriculum integrating language arts, mathematics, science, and social studies using learning stations. This model supports self-directed learning facilitated by responsive adult-initiated adult-child interaction in a play-based environment for nurturing intrinsic motivation and self-directed learning.