The Relationships among Vitamin D Level, Balance, Muscle Strength, and Quality of Life in Postmenopausal Patients with Osteoporosis

Abstract

[Purpose] The aim of this study was to examine the relationships among vitamin D levels, balance, falls, muscular strength, and quality of life in patients with postmenopausal osteoporosis. [Subjects and Methods] Forty-six patients diagnosed with postmenopausal osteoporosis and forty-six healthy controls were included in the study. Bone mineral density was determined by DEXA, and functional balance was evaluated the Timed Up and Go (TUG) test, Chair Raising (CRT) test, Berg Balance Scale (BBS). The muscular strengths were evaluated manually. The lumbosacral region range of motion (ROM) was measured by goniometry. The QUALEFFO-41 questionnaire was used for evaluating the quality of life. [Results] No statistically significant differences in muscular strength, balance, and fall values were found between the two groups. Statistically significant differences were noted between the QUALEFFO C, E, F and G scores and the QUALEFFO total scores of the QUALEFFO-41. Dividing the patient group into two groups revealed that patients with 25(OH)D levels < 15 ng/ml had significantly higher TUG and CRT test scores compared with patients with levels ≥ 15 ng/ml. Also, binary logistic regression analysis revealed that QUALEFFO total scores were found to be the independent factors for osteoporosis. [Conclusion] In this study, we found that vitamin D is necessary to maintain back extensor muscle strength, lumbar ROM, and balance. Our results show that bone mineral density, vitamin D level, balance, lumbar ROM, and the specified muscular strengths are factors that affect the quality of life.

Health‐related quality of life and its associated factors among outpatients with osteoporosis

“…The current study results showed that participants who were found to have lower level of serum Vitamin D were found to have poor HRQoL. Consistent with the current study finding, Korkmaz et al revealed in a randomised controlled trial that HRQoL was significantly lower in postmenopausal women who had low serum vitamin D than those who had normal vitamin D level. A study conducted by Mastaglia et al showed that vitamin D levels should be ≥20 ng/ml to achieve optimal muscle strength and function.…”

Association of hypovitaminosis D with triceps brachii muscle fatigability among older women: Findings from the EPIDOS cohort

“…However, it is noticeable that previous clinical studies on hypovitaminosis D and muscle strength have shown conflicting results [5]. Some cross-sectional studies reported decreased muscle strength in the case of hypovitaminosis D [6,7], although others did not find any significant association [8,9]. Moreover, a meta-analysis of interventional trials showed that vitamin D supplementation could not enhance muscle strength after 9 months of supplementation on average [5].…”

Fatores de risco associados a quedas em idosas: um enfoque preventivo

“…Um estudo realizado com 46 pacientes do sexo feminino, pós-menopausa, com osteoporose, mostrou similares resultados quanto à força muscular e à qualidade de vida, correlacionadas também a outros fatores de risco para quedas (KORKMAZ et al, 2014).…”