The relationships between surgical histometry, outcome and pre-treatment in Graves' disease

Wilkin, Terence J.; Gunn, A.; Moussa, Mohamed A. R.; Isles, T. E.; Crooks, J.; Beck, J. Swanson

doi:10.1530/acta.0.0980043

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…Two studies addressing the histologic cellular composition and antibody production were considered not clinically relevant and were excluded. 15,16 Eleven studies were included in the qualitative synthesis; 2 were further excluded from the quantitative analysis. One randomized controlled study reported no difference in mean blood loss between the groups but did not have details sufficient for analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Among full‐text articles assessed for eligibility, the most common reason for exclusion was that the study was not designed to compare the preoperative administration of any iodine‐containing regimen and no premedication. Two studies addressing the histologic cellular composition and antibody production were considered not clinically relevant and were excluded 15,16 . Eleven studies were included in the qualitative synthesis; 2 were further excluded from the quantitative analysis.…”

Section: Resultsmentioning

confidence: 99%

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Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta‐analysis

Tsai

Yang

Lee

et al. 2019

Otolaryngol.--head neck surg.

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Objective The current guidelines recommend that potassium iodide be given in the immediate preoperative period for patients with Graves’ disease who are undergoing thyroidectomy. Nonetheless, the evidence behind this recommendation is tenuous. The purpose of this study is to clarify the benefits of preoperative iodine administration from published comparative studies. Data Sources We searched PubMed, Embase, Cochrane, and CINAHL from 1980 to June 2018. Review Methods Studies were included that compared preoperative iodine administration and no premedication before thyroidectomy. For the meta-analysis, studies were pooled with the random-effects model. Results A total of 510 patients were divided into the iodine (n = 223) and control (n = 287) groups from 9 selected studies. Preoperative iodine administration was significantly associated with decreased thyroid vascularity and intraoperative blood loss. Significant heterogeneity was present among studies. We found no significant difference in thyroid volume or operative time. Furthermore, the meta-analysis showed no difference in the risk of postoperative complications, including vocal cord palsy, hypoparathyroidism/hypocalcemia, and hemorrhage or hematoma after thyroidectomy. Conclusion Preoperative iodine administration decreases thyroid vascularity and intraoperative blood loss. Nonetheless, it does not translate to more clinically meaningful differences in terms of operative time and postoperative complications.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta‐analysis

Tsai

Yang

Lee

et al. 2019

Otolaryngol.--head neck surg.

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show abstract

“…The support in the literature for this finding is mixed. Some agree, while others disagree [17][18][19][20][21].…”

Section: Hypothyroidism After Subtotal Thyroidectomy For Graves' Dise...mentioning

confidence: 99%

Overview of Surgical Pathology of the Thyroid Gland

Nishiyama

2000

World j. surg.

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The purpose of this overview is to provide timely information on selected topics on the surgical pathology of the thyroid gland. Selected publications of the author and his colleagues at the University of Michigan and the Maine Medical Center form the basis of this review. Information provided in our reports is updated by perusal of recent, pertinent publications. The following questions summarize the contents of the overview. What is a "lateral aberrant thyroid"? Does it always represent metastatic carcinoma? What are dyshormogenetic goiters? Can "focal thyroiditis" in thyroid glands removed for the treatment of Graves' disease and toxic nodular goiters be predictive of the development of postoperative hypothyroidism? What is the pathology of autonomously functioning (hot) nodules? Do tall-cell, columnar-cell, and diffuse sclerosing types of papillary carcinomas forbode bad prognoses? What is the controversy over Hurthle cell tumors? Does the presence of a better differentiated component in an anaplastic thyroid carcinoma modify its biologic behavior? Are poorly differentiated carcinomas unique histologic variants? Does their histology affect prognosis? What is the most common small-cell tumor of the thyroid gland? Has the Chernobyl nuclear disaster affected the incidence of childhood thyroid carcinoma? Are these radiation-induced tumors more aggressive? The answers, some of which are controversial, are found in this overview. The aims here were to provide information to surgeons and pathologists and to improve the care of patients with thyroid disease.

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Surgery for Thyroid Disease

Weber

Clark

1985

Medical Clinics of North America

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The relationships between surgical histometry, outcome and pre-treatment in Graves' disease

Cited by 5 publications

References 11 publications

Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta‐analysis

Effects of Preoperative Iodine Administration on Thyroidectomy for Hyperthyroidism: A Systematic Review and Meta‐analysis

Overview of Surgical Pathology of the Thyroid Gland

Surgery for Thyroid Disease

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