The relative risk of aortic aneurysm in patients with giant cell arteritis compared with the general population of the UK

Robson, Joanna; Kiran, Amit; Maskell, Joe; Hutchings, Andrew; Arden, N K; Dasgupta, Bhaskar; Hamilton, William; Culliford, David; Emin, A; Luqmani, Raashid

doi:10.1016/j.lpm.2013.02.052

Cited by 28 publications

(33 citation statements)

References 5 publications

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“…Smoking and male gender are independent predictors for aortic aneurysm in both GCA and non-GCA cohorts. 2 A previous case report from our institution presented a young woman, under treatment for HIV, who was found to have symptomatic dilatation of aortic root and severe AR. She underwent aortic valve and root replacement, and the histopathology examination showed GCA.…”

Section: Discussionmentioning

confidence: 99%

Giant cell aortitis in treatment-naive human immunodeficiency virus and hepatitis C coinfection

Konstantinidou

Nelson

Rosendahl

et al. 2016

annals

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Giant cell arteritis is a common form of vasculitis, although involvement of the aorta is unusual. There is no established association between giant cell aortitis and human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection. We present the case of a 46-year-old female coinfected with HIV and HCV who had never received antiretroviral therapy and developed symptoms of deteriorating shortness of breath on exertion. Investigations demonstrated aortic root and ascending aorta dilatation, along with severe aortic valve regurgitation, for which the patient underwent valve-sparing aortic root replacement (a David procedure). Histopathology confirmed giant cell aortitis.

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Section: Discussionmentioning

confidence: 99%

Giant cell aortitis in treatment-naive human immunodeficiency virus and hepatitis C coinfection

Konstantinidou

Nelson

Rosendahl

et al. 2016

annals

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“…Patients with GCA have a 6.6–17.3‐fold increased risk of developing thoracic aortic aneurysm compared with the general population . Aortic aneurysm is a delayed complication of GCA (22.2% and 33.3% of patients with GCA after a median disease duration of 5.4 and 10.3 years, respectively) .…”

Section: Discussionmentioning

confidence: 99%

Large‐Vessel Dilatation in Giant Cell Arteritis: A Different Subset of Disease?

Muratore

Kermani

Crowson

et al. 2018

Arthritis Care & Research

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“…Giant cell (temporal) arteritis and other autoimmune disorders have been associated with TAA (51)(52)(53). A population-based cohort study from Olmstead County (Minnesota) showed that patients with temporal arteritis were 17 times more likely to develop a TAA than patients without this condition (54).…”

Section: Temporal Arteritis (And Other Autoimmune Disorders)mentioning

confidence: 99%

Guilt by association: a paradigm for detection of silent aortic disease

Ziganshin¹,

Elefteriades²

2016

Ann. Cardiothorac. Surg.

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Detection of clinically silent thoracic aortic aneurysm (TAA) is challenging due to the lack of symptoms (until aortic rupture or dissection occurs). A large proportion of TAA are identified incidentally while imaging a patient for other reasons. However, recently several clinical "associates" of TAA have been described that can aid in identification of silent TAA. These "associates" include intracranial aneurysm, aortic arch anomalies, abdominal aortic aneurysm (AAA), simple renal cysts (SRC), bicuspid aortic valve, temporal arteritis, a positive family history of aneurysm disease, and a positive thumb-palm sign. In this article we examine these associates of TAA and the data supporting their involvement with asymptomatic TAA.

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The relative risk of aortic aneurysm in patients with giant cell arteritis compared with the general population of the UK

Cited by 28 publications

References 5 publications

Giant cell aortitis in treatment-naive human immunodeficiency virus and hepatitis C coinfection

Giant cell aortitis in treatment-naive human immunodeficiency virus and hepatitis C coinfection

Large‐Vessel Dilatation in Giant Cell Arteritis: A Different Subset of Disease?

Guilt by association: a paradigm for detection of silent aortic disease

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