The Relevance of High Pulse Pressure and Renal Function in Patients with Chronic Kidney Disease: Analysis for each Stage of Chronic Kidney Disease

Abstract

In the present study, we retrospectively investigated consecutive patients who visited the Nephrology Medicine Department of Yokosuka Kyousai Hospital between September 2006 and October 2011. In total, our study included 104 participants with CKD (stage G3a-G5) who were diagnosed with hyperlipidemia and commenced on high potency statins. The average normal PP is 50 mmHg, and the risk of CVD increases when PP is ≥65 mmHg [11]. The participants were categorized on the basis of their PP: ≥65 mmHg was the High PP group, and PP <65 mmHg was the Low PP group. Investigation itemsData regarding the participants' basic information were collected from their medical records at baseline and 12 months later, as appropriate. This included their age, gender, body weight (BW), body mass index (BMI), smoking history, comorbidity (e.g., diabetes mellitus, hypertension). Laboratory data, including the levels of SBP, DBP, aspartate aminotransferase (AST), alanine aminotransferase (ALT), serum uric acid (SUA), blood urea nitrogen (BUN), serum

Association of pulse pressure and CVD Incidence rate: a cohort study of a Chinese population

“…Meanwhile, pulse pressure is closely related to SBP and DBP [4] and increases gradually with age [5,6] . Previous studies have demonstrated an association of PP with several adverse outcomes such as type 2 diabetes mellitus (T2DM) [7] , metabolic syndrome [8] , cardiovascular events [9] [10] [11] , stroke [12] , chronic kidney disease [13] and even death [14, 15] [16] .…”