“…Among 21 studies included in the meta-analysis, 39 different modalities were identified in terms of pupil status, retinal field strategy and human resources involved in index test DR grading. Forty-six percent (18/39 modalities) of the studies used non-mydriatic methods (13/21 studies) [ 25 , 26 , 29 , 31 , 35 , 38 , 40 , 42 , 44 , 45 , 47 – 49 ], 44% (17/39 modalities) used mydriatic methods (11/21 studies) [ 23 – 25 , 32 , 35 , 37 , 39 , 40 , 42 , 44 , 47 ] and ophthalmic personnel currently trained and practiced in DR grading had performed index test grading in these studies. In 10%, 4/21 [ 27 , 28 , 46 , 48 ] newer non-ophthalmologist personnel had performed index test grading.…”