The remarkable impact of bivalent HPV vaccine in Scotland

Brotherton, Julia

doi:10.1136/bmj.l1375

Cited by 5 publications

(4 citation statements)

References 10 publications

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“…The same 2 members of the research team compared their classifications and scoring, and if consensus could not be reached, a third member of the research team (LKAS) made the final decision. In addition, we extracted information about the characteristics of the paper (study design, research question, or objective), journal (journal name and year published), and author (names, affiliations, and conflicts of interest; refer to Multimedia Appendices 1 and 2 [52,[71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88][89] for results of the top 20 most shared papers obtained from the vaccine-confident and vaccine-hesitant communities). These data were used to conduct bibliometric analyses of the journal and descriptive analysis of the research content shared by each community, which are further described in the following sections.…”

Section: Typology Of Evidence For Thematic and Critical Appraisalmentioning

confidence: 99%

“…For example, in the orange cluster, 1 particularly influential physician circulated an editorial paper about the effectiveness of the HPV vaccine, which indicated that high HPV vaccine coverage could eradicate cervical cancer within a few decades [74]. A science correspondent for a pre-eminent American newspaper was the leading influencer in the light green cluster wherein the primary paper circulated was an editorial, also focused on effectiveness, related to the positive impacts of HPV vaccination in Scotland [75]. Finally, in the blue cluster, a leading cancer prevention researcher from a British research institute was the leading influencer and author of the scientific papers circulated.…”

Section: Vaccine-confident Social Networkmentioning

confidence: 99%

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The Role of Scientific Research in Human Papillomavirus Vaccine Discussions on Twitter: Social Network Analysis

Jessiman-Perreault,

Boucher,

Kim

et al. 2024

JMIR Infodemiology

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Background Attitudes toward the human papillomavirus (HPV) vaccine and accuracy of information shared about this topic in web-based settings vary widely. As real-time, global exposure to web-based discourse about HPV immunization shapes the attitudes of people toward vaccination, the spread of misinformation and misrepresentation of scientific knowledge contribute to vaccine hesitancy. Objective In this study, we aimed to better understand the type and quality of scientific research shared on Twitter (recently rebranded as X) by vaccine-hesitant and vaccine-confident communities. Methods To analyze the use of scientific research on social media, we collected tweets and retweets using a list of keywords associated with HPV and HPV vaccines using the Academic Research Product Track application programming interface from January 2019 to May 2021. From this data set, we identified tweets referring to or sharing scientific literature through a Boolean search for any tweets with embedded links, hashtags, or keywords associated with scientific papers. First, we used social network analysis to build a retweet or reply network to identify the clusters of users belonging to either the vaccine-confident or vaccine-hesitant communities. Second, we thematically assessed all shared papers based on typology of evidence. Finally, we compared the quality of research evidence and bibliometrics between the shared papers in the vaccine-confident and vaccine-hesitant communities. Results We extracted 250 unique scientific papers (including peer-reviewed papers, preprints, and gray literature) from approximately 1 million English-language tweets. Social network maps were generated for the vaccine-confident and vaccine-hesitant communities sharing scientific research on Twitter. Vaccine-hesitant communities share fewer scientific papers; yet, these are more broadly disseminated despite being published in less prestigious journals compared to those shared by the vaccine-confident community. Conclusions Vaccine-hesitant communities have adopted communication tools traditionally wielded by health promotion communities. Vaccine-confident communities would benefit from a more cohesive communication strategy to communicate their messages more widely and effectively.

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Section: Typology Of Evidence For Thematic and Critical Appraisalmentioning

confidence: 99%

Section: Vaccine-confident Social Networkmentioning

confidence: 99%

The Role of Scientific Research in Human Papillomavirus Vaccine Discussions on Twitter: Social Network Analysis

Jessiman-Perreault,

Boucher,

Kim

et al. 2024

JMIR Infodemiology

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“…But, four patients who had apparent anaphylactic reactions to it were negative skin test to vaccine, baker's yeast, and polysorbate 80. Vaccination in adolescents was associated with a high rate of syncope that accounted for some events diagnosed as anaphylaxis (Brotherton, 2019) Influenza: Some vaccines contain egg protein, but allergic reactions were due to some other components as well. In Japan in 2011 & 2012, there was a three-to fivefold increase in influenza vaccine-associated anaphylaxis reported in 36 children without egg allergy, of whom 19 were subsequently investigated (Nagao et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

An Overview on Allergic Reactions to Pathogenic Vaccines

HAWAM,

ABOU-ELMAGD,

ELSHISHTAWY

et al. 2023

Journal of the Egyptian Society of Parasitology

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A pathogen is a bacterium, virus, parasite or fungus that inhabits virtually every environment on the planet and can cause diseases to man, animals and plants. Vaccines contain weakened or inactive parts of a particular organism (antigen) that triggers an immune response within the body. Newer vaccines contain the blueprint for producing antigens rather than the antigen itself. Regardless of whether the vaccine is made up of the antigen itself or the blueprint so that the body will produce the antigen, which will not cause the disease in the person receiving the vaccine, but it will prompt the immune system to respond much as it would have on its first reaction to the actual pathogen. They help to create protective antibodies-proteins help in fighting off infections. But, vaccine refusal may result in vaccine-preventable disease in individual and/or outbreaks of vaccine-preventable disease in unvaccinated and vaccinated individuals However, severe allergic reactions to vaccines are rare but do occur. Local reactions involved redness, swelling or irritation at the injection site. These common reactions typically begin within a few hours of the injection and clear up soon after. Systemic ones, which are less common, but potentially more serious develop sneezing, nasal congestion or hives or even throat swelling, wheezing or chest tightness. Anaphylaxis is a rare life-threatening reaction to allergy shots as low blood pressure and trouble breathing begins within 30 minutes of the injection, or even starts later than that.The vast majority of microbes are harmless, and many play essential roles in plant, animal and human health. This overview focuses on immediate-type allergic reactions to human vaccines; and delayed reactions are also briefly discussed overview discussed. The overview on allergic reactions to the new developed parasitic vaccines will be given in due time elsewhere.

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“…Further, a more complete picture of HPV infection age-patterns may provide parameters to better understand the global nature of HPV infection and the impact of HPV vaccination in future screening cohorts. [7][8][9] Additionally, it is relevant to evaluate the differences of age at the triage step in settings where a second test is used to detect precancerous lesions among HPV-positive women. When using HPV as the primary screening test, a certain proportion of women may not develop disease as they may clear the infection.…”

Section: Introductionmentioning

confidence: 99%

Age patterns of human papillomavirus infection as primary screening test for cervical cancer and subsequent triage with visual inspection in Honduras

Sandoval

Holme²,

Lobo³

et al. 2020

Salud Publica Mex

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Objective. To evaluate age patterns in human papillomavirus (HPV) prevalence and visual inspection with acetic acid (VIA) positivity among women participating in cervical cancer screening in Honduras. Materials and methods. Data on the HPV status (careHPV) and subsequent VIA in HPV-positive women were retrieved from three provinces within the Public Health Sector. Results. Between 2015 and 2018, 60 883 women aged 15-85 years were screened. HPV was detected in 15%, with variation by age, peaking at 20-24 years (27.8%) decreasing to 16% at 30-49 years. Differences in point age– specific HPV prevalence were observed between provinces, but with similar age pattern. VIA was positive in 24.5% of the women aged 30-44 years. Conclusions. The age pattern of the HPV prevalence supports starting HPV testing at age 30+. The low positivity of VIA in ages close to menopause suggest underdetection of cervical lesions in this age group.

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The remarkable impact of bivalent HPV vaccine in Scotland

Abstract: New analyses show substantial cross protection and herd immunity

Cited by 5 publications

References 10 publications

The Role of Scientific Research in Human Papillomavirus Vaccine Discussions on Twitter: Social Network Analysis

The Role of Scientific Research in Human Papillomavirus Vaccine Discussions on Twitter: Social Network Analysis

An Overview on Allergic Reactions to Pathogenic Vaccines

Age patterns of human papillomavirus infection as primary screening test for cervical cancer and subsequent triage with visual inspection in Honduras

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