The Reply

Pelliccia, Francesco; Rosano, Giuseppe

doi:10.1016/j.amjmed.2014.11.014

Cited by 14 publications

(3 citation statements)

References 7 publications

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“…In our population with TTC, similarly to data from the literature, we observed less cardiovascular risk factors than in patients with anterior STEMI but more cases of COPD (11.6 %) and thyroid disturbances (23.4 %), mainly hyperthyroidism [5]. …”

Section: Discussionsupporting

confidence: 86%

“…We observed chest pain in 83 % of our patients. In other studies chest pain typical for MI was observed in 54–100 % of the patients with TTC [5]. …”

Section: Discussionmentioning

confidence: 91%

“…[13] 86 % were women; the mean age was 67. In other published data, women account for 80–100 % of the population with a mean age of 61–76 years [5, 14]. It is worth noting that TTC may also be diagnosed in younger women.…”

Section: Discussionmentioning

confidence: 99%

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Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Zalewska-Adamiec

Bachórzewska−Gajewska

Tomaszuk‐Kazberuk

et al. 2016

Neth Heart J

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BackgroundTakotsubo cardiomyopathy (TTC) is characterised by transient contractility disturbances of the apex of the left ventricle.MethodsWe enrolled 101 patients from the northern-eastern part of Poland in the years 2008–2012 who were hospitalised for TCC. The control group consisted of female patients diagnosed with anterior myocardial infarction with ST-segment elevation (anterior STEMI) (n = 101).Results89 % of the study group were women. Patients with TTC had diabetes (12.6 % vs 29.7 %; p = 0.002) and hyperlipidaemia (36.8 % vs 64.4 %; p = 0.0001) significantly less frequently, and better kidney function assessed by estimated glomerular filtration rate versus patients with anterior STEMI (74.52 % vs 64.30 %; p = 0.004). In the TTC group there were more patients with chronic obstructive pulmonary disease (11.6 % vs 1.0 %; p = 0.002) and thyroid disturbances, especially hyperthyroidism (23.4 % vs 11.0 %; p = 0.021). In patients with TTC sudden cardiac arrest, pulmonary oedema and cardiogenic shock were observed less frequently than in the control group (14.7 % vs 30.7 %; p = 0.0078). Hospitalisations in TTC patients were less frequently complicated by pneumonia (20.0 % vs 35.6 %; p = 0.0148) and urinary infection (4.2 % vs 21.8 %; p = 0.0003). Cardiac rupture occurred in 3 patients with TTC and in 1 with anterior STEMI. In-hospital mortality was significantly lower in the group with TTC. Also, mortality at 30 days, 3 months, 1 year and 2.5 years was significantly lower in patients with TTC than in patients with MI (p = 0.035; p = 0.0226; p = 0.0075; p = 0.009).ConclusionsPreviously considered to be a benign syndrome, TTC should be reconsidered as a clinical condition at risk for serious complications such as cardiac arrest, cardiogenic shock, pulmonary oedema and cardiac rupture leading to death and causing substantial early hazard. The prognosis in TTC is significantly better than in patients with anterior STEMI.

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Section: Discussionsupporting

confidence: 86%

“…We observed chest pain in 83 % of our patients. In other studies chest pain typical for MI was observed in 54–100 % of the patients with TTC [5]. …”

Section: Discussionmentioning

confidence: 91%

See 1 more Smart Citation

Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Zalewska-Adamiec

Bachórzewska−Gajewska

Tomaszuk‐Kazberuk

et al. 2016

Neth Heart J

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Doxorubicin‐associated takotsubo cardiomyopathy in a patient with adult T‐cell leukemia/lymphoma

Mubarak

Haddadin

Samra

et al. 2019

Clinical Case Reports

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This case highlights the first reported association of doxorubicin with takotsubo cardiomyopathy (TC) presenting as cardiogenic shock during the first continuous infusion in a patient with adult T‐cell leukemia/lymphoma. We aim to raise awareness to recognize and distinguish between irreversible doxorubicin‐associated cardiomyopathy and reversible doxorubicin‐associated TC in patients with cancer.

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Differential Diagnosis of TGA

Larner

2022

Transient Global Amnesia

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The Reply

Cited by 14 publications

References 7 publications

Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Takotsubo cardiomyopathy: serious early complications and two-year mortality – a 101 case study

Doxorubicin‐associated takotsubo cardiomyopathy in a patient with adult T‐cell leukemia/lymphoma

Differential Diagnosis of TGA

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