The resectability of primary lung carcinoma: A diagnostic staging review

Hirleman, Michael T.; Yiu-Chiu, Victoria S.; Chiu, Lee C.; Schapiro, Rolf L.

doi:10.1016/s0149-936x(80)80009-9

Cited by 18 publications

(9 citation statements)

References 12 publications

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“…However, Fishman and Bronstein (1975) found that lymph node involvement was detected by mediastinoscopy in 28% of a group of patients in whom mediastinal tomography failed to reveal metastases. More recent studies (Hirleman et al, 1980;Osborne et al, 1982) have demonstrated a sensitivity of 50-75% for conventional mediastinal tomography in identifying positive nodes. The greater sensitivity of computerized tomography (CT) in this respect (vide infra) suggests a role for noninvasive staging in selecting for mediastinoscopy only those patients in whom enlarged mediastinal nodes are demonstrated.…”

Section: Mediastinoscopy and Mediastinotomymentioning

confidence: 98%

“…Several reports have compared CT with conventional tomography as preoperative staging procedures (Hirleman et al, 1980;Mintzer et al, 1979;Osborne et al, 1982), with definitive staging achieved by thoracotomy, mediastinoscopy or at autopsy. In the study by Mintzer and colleagues (1979), CT demonstrated mediastinal adenopathy in 12 of 16 (75%) patients subsequently shown to have mediastinal disease at surgery.…”

Section: Conventional and Computed Mediastinal Tomographymentioning

confidence: 99%

“…However, conventional tomography appeared to be as sensitive as CT in disclosing hilar lymphadenopathy. Tables 1 and 2 summarize the comparative data from the investigations by Hirleman et al (1980) andOsborne et al (1982). Both studies demonstrate the greater sensitivity of CT for mediastinal evaluation, but also its poorer specificity.…”

Section: Conventional and Computed Mediastinal Tomographymentioning

confidence: 99%

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Pre-operative mediastinal evaluation in primary bronchial carcinoma—a review of staging investigations

Elliott

1984

Postgraduate Medical Journal

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Summary A review of staging investigations in the preoperative evaluation of mediastinal involvement in primary bronchial carcinoma is presented. The following conclusions are offered as guidelines for the use of mediastinal staging procedures in clinical practice: Surgical staging methods have the over-riding advantage of superior specificity over indirect imaging techniques. Where 67Ga-imaging or CT scanning are not available, routine pre-operative mediastinoscopy or, when appropriate, mediastinotomy will identify most patients with non-resectable disease but this approach entails a high proportion of true negative examinations. Radioisotope ventilation and perfusion lung imaging has no place in the pre-operative staging of lung cancer. Where the techniques are available, 67Ga-imaging and CT scanning have a use in selecting patients for mediastinal exploration. A negative mediastinal 67Ga scan or a negative CT examination suggest that mediastinal exploration will be unrewarding in the vast majority of cases and may be omitted prior to thoracotomy. A positive mediastinal 67Ga scan or the demonstration of abnormal mediastinal nodes by CT is an indication for mediastinal exploration which, if negative should be followed by thoracotomy.

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Section: Mediastinoscopy and Mediastinotomymentioning

confidence: 98%

Section: Conventional and Computed Mediastinal Tomographymentioning

confidence: 99%

Section: Conventional and Computed Mediastinal Tomographymentioning

confidence: 99%

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Pre-operative mediastinal evaluation in primary bronchial carcinoma—a review of staging investigations

Elliott

1984

Postgraduate Medical Journal

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“…This point, raised by Hirleman et al [13], must be addressed so that "large" nodes in these circumstances are not considered abnormal a priori.…”

Section: Criteria Sensitivity and Specificitymentioning

confidence: 99%

CT of mediastinal lymph nodes in lung cancer: is there a "state of the art"?

Libshitz¹

1983

American Journal of Roentgenology

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“…Since the introduction of routine body CT scanning in the 1970s, CT has been the imaging mainstay for lung cancer staging [1][2][3]. However, there is variability from institution to institution in the anatomic extent of scanning performed for lung cancer staging.…”

Section: Introductionmentioning

confidence: 99%