The Respiration of the Salivary Microbial Flora and its Relation to Dental Caries Activity

Spatially and temporally resolved metabolome of the human oral cavity

“… 36 Increased oxygen uptake by bacteria has been suggested to promote the aerobic degradation of glucose and further oxidation of lactic acid into less harmful substances when referring to dental caries. 37 , 38 In turn, L-ornithine could be a biomarker for healthy teeth. As an exception to the spatial patterns described above, N-acetyl aspartate and acetyl carnitine were found to be characteristic of CK rather than AT, whereas metabolically related metabolites, N-acetyl asparagine, and deoxy carnitine showed a reverse spatial distribution ( Figure S4 ).…”

Caries‐susceptibility Tests

“…(Sellman, 1950;Snyder et al, 1962;Snyder et al, 1963). Another method measures the oxygen uptake of saliva in the absence (Kroncke & Naujoks, 1956) or presence (Green et al, 1959) of substrate by manometric techniques. Kroncke and Naujoks (1956) claimed a n oxygen uptake much greater in mouths with little caries activity than in mouths that were caries active.…”