Journal of Urology

2001

DOI: 10.1097/00005392-200101000-00062

|View full text |Cite

|

Sign up to set email alerts

|

The Response of Balanitis Xerotica Obliterans to Local Steroid Application Compared With Placebo in Children

¹

,

²

,

³

et al.

Abstract: Applying a potent topical steroid affects improvement in balanitis xerotica obliterans in the histologically early and intermediate stages of disease, and may inhibit further worsening in the late stage.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction3

Discussion1

Lichen Sclerosus/bxo1

Citation Types

Supporting

0

Mentioning

82

Contrasting

0

Unclassified

3

Year Published

2004

2004

2024

2024

Publication Types

Select...

Article7

Book1

Other1

Relationship

Self Cite0

Independent9

Authors

Journals

Cited by 104 publications

(85 citation statements)

References 13 publications

Supporting

0

Mentioning

82

Contrasting

0

Unclassified

3

Order By: Relevance

“…Because BXO had been regarded as an adult disease for a long time, current literature differs from older literature regarding the incidence of BXO in children [7]. Recently, researchers have indicated that BXO may be an etiological factor for up to 20% of phimosis cases in boys [8,9,10]. This new data indicates a significantly higher incidence of BXO than that previously reported.…”

Section: Introductionmentioning

confidence: 84%

“…Data indicates that the application of a potent topical steroid cream results in improvement in BXO in the histopathologically early and intermediate stages of the disease. Furthermore, topical steroid therapy has been reported to slow down the progression of the disease [6,9,17]. Circumcision is the treatment of choice for clinically suspected BXO, because this procedure may be curative.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

¹

,

²

,

³

et al. 2012

View full text Add to dashboard Cite

Objective: Evaluation of the true incidence of balanitis xerotica obliterans (BXO) among boys younger than 10 years. Methods: In a period of 13 months, 75 boys younger than 10 years were treated for phimosis. Suspicion of BXO was raised in phimosis grade 2 or 3 (classification by Kikiros). Patients were offered primarily either circumcision or conservative therapy and circumcision secondarily (if treatment failed in the conservative group). Each circumcision specimen was examined histopathologically. Results: Circumcision was primarily performed in 29 and secondarily in 17 patients. The mean age was 3.7 years (range 1-10). BXO, chronic inflammation, and normal histological results were found in 8/26/12 (17.4/56.5/26.1%) cases, respectively. The mean follow-up was 8.1 months. No recurrences were reported. Conclusions: The incidence of BXO appears to be higher than previously reported. The clinical appearance in children may be confusing. The preoperative BXO suspicion did not correlate with the final histopathological results.

“…Because BXO had been regarded as an adult disease for a long time, current literature differs from older literature regarding the incidence of BXO in children [7]. Recently, researchers have indicated that BXO may be an etiological factor for up to 20% of phimosis cases in boys [8,9,10]. This new data indicates a significantly higher incidence of BXO than that previously reported.…”

Section: Introductionmentioning

confidence: 84%

“…Data indicates that the application of a potent topical steroid cream results in improvement in BXO in the histopathologically early and intermediate stages of the disease. Furthermore, topical steroid therapy has been reported to slow down the progression of the disease [6,9,17]. Circumcision is the treatment of choice for clinically suspected BXO, because this procedure may be curative.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Balanitis Xerotica Obliterans in Boys Younger than 10 Years Presenting with Phimosis

¹

,

²

,

³

et al. 2012

View full text Add to dashboard Cite

Objective: Evaluation of the true incidence of balanitis xerotica obliterans (BXO) among boys younger than 10 years. Methods: In a period of 13 months, 75 boys younger than 10 years were treated for phimosis. Suspicion of BXO was raised in phimosis grade 2 or 3 (classification by Kikiros). Patients were offered primarily either circumcision or conservative therapy and circumcision secondarily (if treatment failed in the conservative group). Each circumcision specimen was examined histopathologically. Results: Circumcision was primarily performed in 29 and secondarily in 17 patients. The mean age was 3.7 years (range 1-10). BXO, chronic inflammation, and normal histological results were found in 8/26/12 (17.4/56.5/26.1%) cases, respectively. The mean follow-up was 8.1 months. No recurrences were reported. Conclusions: The incidence of BXO appears to be higher than previously reported. The clinical appearance in children may be confusing. The preoperative BXO suspicion did not correlate with the final histopathological results.

“…The term lichen sclerosus et atrophicans describes a chronic inflammatory skin disorder, whereas the term balanitis xerotica obliterans describes the occurrence of lichen sclerosus et atrophicans on the penile skin. The prevalence of penile lichen sclerosus et atrophicans is in the range of 1/300 to 1/1,000 in adults, but in children it is probably higher (10-14% of children phimosis scheduled for circumcision) [7] .…”

Section: Introductionmentioning

confidence: 99%

Long-Term Efficiency of Skin Stretching and a Topical Corticoid Cream Application for Unretractable Foreskin and Phimosis in Prepubertal Boys

¹

,

²

,

2009

View full text Add to dashboard Cite

Objectives: To evaluate the long-term efficacy of topical application of a potent corticoid cream and skin stretching in the treatment of unretractable foreskin, pinpoint phimosis, balanopreputial adhesions and lichen sclerosus in prepubertal boys. Methods: 462 prepubertal boys (mean age 4.7 years) with unretractable foreskin applied a topical potent corticoid cream together with skin stretching twice daily for 6 weeks. Follow-up interview of all patients was performed to evaluate long-term results (median 22 months). Short- and long-term results were compared and evaluated. Results: 400/462 boys (86%) had a retractable prepuce after 6 weeks of treatment. 62/462 boys had no or only a partial response. After a median follow-up of 22 months, the treatment continued to be successful in 383/462 boys (83%). In 76/462 boys the foreskin was unretractable, of which 35 preferred surgical treatment. 12/462 boys presented with lichen sclerosus and the non-surgical treatment appeared efficient in 9/12 (67%). Conclusions: This study has shown that local application of a potent corticoid cream and skin stretching is a safe, simple and effective long-term treatment for all types of unretractable foreskin in prepubertal boys. The efficiency of the treatment was not related to the age of the patient or the type of unretractable foreskin.

“…3 While most of the patients who present with the same are asymptomatic, a small proportion of children does have symptoms like ballooning, dribbling, balanoposthitis or even urinary tract infections. 4 Older children may present differently with pain during erection.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Neosporin hydrocortisone cream versus preputial dilatation in children with phimosis: a comparative study

2017

View full text Add to dashboard Cite

Background: Physiological phimosis, a common complaint in the pediatric surgery outpatient department presenting as non-retractile foreskin is due to adhesions between the inner layer of the prepuce with glans penis or due to tight tip of the prepuce. These patients are managed with circumcision, preputial dilatation. In this study, we compare different outcomes measures in children treated with dilatation and those with application of Neosporin-hydrocortisone ointment.Methods: This prospective comparative study was conducted in the department of pediatric surgery outpatient department between 2015 and 2017. We followed up 50 patients who underwent only dilatation and other 66 patients who were advised to apply only hydrocortisone impregnated antibiotic cream twice daily over a period of six weeks. We recorded basic demographic features, parent anxiety, parental compliance, parent satisfaction, complete response and persistence of phimosis at the end of the treatment. All statistical tests were done using R statistical software.Results: Of the 116 children recruited to the study, 50(43%) belonged in the dilatation group and rest (66%) to the Neosporin-hydrocortisone (NH) group. The median age of the patients was 36 with inter-quartile range (23-48) months. Baseline characteristics were comparable across the groups. At the end of six weeks, there was statistically significant difference between the two groups with regard to all outcome measures namely parent compliance, parent satisfaction, symptom resolution with the NH group showing a better result (P value<0.0001). Moreover, Phimosis persisted in 18 (36%) of the patients treated with dilatation compared to 4 (6%) in Neosporin hydrocortisone ointment group which was statistically significant.Conclusions: Present study shows that local application of Neosporin-hydrocortisone ointment is a better alternative to using the painful preputial dilatation in children with phimosis.

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Product

Browser Extension Assistant by scite Citation Statement Search Reference Check Visualizations Dashboards Explore Journals Explore Organizations Explore Funders Embedding Badge Embedding Citation Search Pricing

Resources

Blog Help & FAQ Accessibility Statement API Terms For Universities & Governments For Researchers For Publishers For Corporate, Pharma & Enterprise Author Marketing Become an Affiliate Get an organization trial or quote scite Data & Services

About

News & Press Careers Read our Paper Coverage

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Copyright © 2024 scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.