The response of leukocyte subsets and plasma hormones to interval exercise

Gray, A. B.; Telford, Rohan M.; Collins, Michael; Weidemann, Maurice J.

doi:10.1249/00005768-199311000-00008

Cited by 25 publications

(29 citation statements)

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“…The numbers of granulocytes, lymphocytes and monocytes have been reported to be increased after exercise [1][2][3][4][5][6][7][8][9][10][11][12] , but the numbers of samples in these studies were too small to come up with a consensus. In addition, effects of exercise on gender differences are surprisingly unclear.…”

Section: Discussionmentioning

confidence: 99%

“…This increase could be due to potentiating the sheer blood flow that occurs during this sort of exercise as previously described [17] . It could also be due to the release of catecholamine which was reported to be increased in plasma after intensive short-term exercise [8,11] . We also noted a similar pattern of cell accumulation in the blood circulation of males and females performing similar activity, suggesting that there are no gender differences in relation to neutrocytosis, lymphocytosis or monocytosis after this type of exercise.…”

Section: Sand Kl Et Al Exercise Affects Leukocytosis and Hemostasismentioning

confidence: 99%

“…Neutrocytosis may depend on the duration rather than the intensity of the exercise, which also depends on the release of adrenocorticotropic hormone [7] . Intensive short-term exercise resulted in increased leukocytosis which included lymphocytes, granulocytes and monocytes concomitant with alterations in plasma catecholamine levels [8] . A 30 min exercise in 8 male volunteers resulted in increased catecholamine and leukocytosis, whereas another round of exercise 3 h later also resulted in enhanced leukocytosis "neutrophils and lymphocytes" and increased cortisol levels [9] .…”

Section: Introductionmentioning

confidence: 99%

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Effects of exercise on leukocytosis and blood hemostasis in 800 healthy young females and males

Sand

Flatebø

Andersen

et al. 2013

WJEM

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AIM:To investigate the effects of exercise on healthy individuals of both genders. METHODS:This study lasted 6 years and involved about 800 healthy people. Individuals were divided into females and males and further sub-divided into two groups; in the first group individuals run (or skied in the winter time) and then rested for 3 h, whereas individuals in the second group intensely cycled for 5 min. The status of health was determined by measuring the sedimentation rate and the intensity of exercises by measuring the heart rate. Blood samples were collected before and after exercise. RESULTS:We observed that in the first group a significant increase of the total white blood cells, segmented neutrophils, band neutrophils, eosinophils and to a lesser extent lymphocytes but not monocytes in the blood circulation. However, all cell types were increased in the circulation after 5 min intense exercise. No differences in the pattern of cell increase were observed among the genders. Activated partial thromboplastin time (APTT) and D-dimer were also measured in the blood of individuals who cycled intensely for 5 min to determine the coagulation and fibrinolytic activities in the blood. APTT is reduced and D-dimer values significantly increased after intense exercise. However, APTT was statistically lower in males than females, whereas no differences in the D-dimer values were observed among the genders. CONCLUSION:Our results indicate that exercise whether leisure or strenuous affects leukocytosis and hemostasis in both genders. A major advantage of this study is the high numbers of individuals involved and the inclusion of both females and males values.

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Section: Discussionmentioning

confidence: 99%

Section: Sand Kl Et Al Exercise Affects Leukocytosis and Hemostasismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of exercise on leukocytosis and blood hemostasis in 800 healthy young females and males

Sand

Flatebø

Andersen

et al. 2013

WJEM

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“…body composition measurements were followed by blood collection and a submaximal exer cise test. Blood samples were taken before exercise in order to avoid exercise-induced hemoconcentration [6], leukocytosis [7,8] …”

Section: Experimental Designmentioning

confidence: 99%

“…The design o f the study was crossover with re peated measurements [8], We resorted to nonparametric tests since it was more convenient due to the pairing o f observations through repeated measurements and the low sample size. The Wilcoxon signed-rank test was used to test the hypothesis o f 'no difference' between two paired observations.…”

Section: Exercise Testsmentioning

confidence: 99%

Effect of Ramadan Fasting on Physical Performance, Blood and Body Composition

1994

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In order to understand the physiological adaptations during Ramadan fasting (RF), we studied the body composition, electrolyte balance, hematological response and physical performance in 15 healthy male Kuwaitis (mean age 37 years). Body composition, biochemical analysis, hematological count and exercise performance were evaluated on four occasions: 1 week before RF, 2 weeks during RF, during the last 4 days of RF, and 1 week to 10 days after RF. Cardiopulmonary exercise was performed on a Monark bicycle ergometer at 100 W for 6–8 min. Body composition was obtained using the skin-fold technique, and biochemical and hematological analyses were done using established standard techniques. Subjects lost 1.2% of their total body weight and 5 % of their body fat weight within 2 weeks of RF (p < 0.05). Total serum proteins, albumin and osmolarity significantly increased (p < 0.05) at the end of RF. White blood cells, platelets and serum iron were significantly decreased at the end of RF (p < 0.05). There was no significant change in red blood cell count and hematocrit during RF. Submaximal heart rate was significantly decreased (p < 0.05) by 5.4% whereas submaximal oxygen uptake increased by 12.7% at the end of RF. There was no significant difference in submaximal minute ventilation during the study period. It is concluded that RF is associated with metabolic, hematologic and cardiopulmonary adaptations which are of paramount importance in this period of restricted fluid, mineral and food intake.

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Acute exercise stimulates macrophage function: possible role of NF‐κB pathways

Silveira

Rodrigues

Krause

et al. 2006

Cell Biochemistry & Function

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Moderate physical activity when performed on a regular basis presents a number of benefits to the whole organism, especially regarding immune system function, such as augmenting resistance to infections and to cancer growth. Although glutamine production by active muscle cells as well as neuroendocrine alterations mediated by the chronic adaptation to exercise may play a role, the entire mechanism by which exercise makes the immune system aware of challenges remains mostly uncovered. This is particularly true for the effects of an acute exercise session on immune function. In this work, circulating monocytes/macrophages from sedentary rats submitted to an acute (1 h) swimming session were tested for the ability of phagocytosing zymosan particles, phorbol miristate acetate (PMA)-induced hydrogen peroxide production, nitric oxide (NO) release (assessed by nitrate and nitrite production) and the expression of NO synthases (NOS-1, NOS-2 and NOS-3). The results showed that an exercise bout induced a 2.4-fold rise in macrophage phagocytic capacity (p ¼ 0.0041), a 9.6-fold elevation in PMA-induced hydrogen peroxide release into the incubation media (1-h, p ¼ 0.0022) and a 95.5%-augmentation in nitrite basal production (1-h incubation; p ¼ 0.0220), which was associated with a marked expression of NOS-2 (the inducible NOS isoform; p ¼ 0.0319), but not in other NOS gene products. Although NOS-2 expression is nuclear factor-kB (NF-kB)-dependent, no systemic oxidative stress was found, as inferred from the data of plasma TBARS and glutathione disulphide (GSSG) to glutathione (GSH) ratio in circulating blood erythrocytes which remained constant after the acute exercise. Also, no stressful situation seemed to be faced by monocytes/macrophages, since the expression of the 70-kDa heat shock protein (HSP70) remained unchanged. We conclude that NF-kB-dependent induction of NOS-2 and macrophage activation must be related to local factor(s) produced in the surroundings of monocytes/macrophages.

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The response of leukocyte subsets and plasma hormones to interval exercise

Cited by 25 publications

References 0 publications

Effects of exercise on leukocytosis and blood hemostasis in 800 healthy young females and males

Effects of exercise on leukocytosis and blood hemostasis in 800 healthy young females and males

Effect of Ramadan Fasting on Physical Performance, Blood and Body Composition

Acute exercise stimulates macrophage function: possible role of NF‐κB pathways

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