In this work, we investigate the ambiguities proposed by Benhar et al. about different implementation of the impulse approximation (IA) for calculation of the response function of many-Fermion system. The many-Fermion wave-function of composite system is calculated in the framework of impulse approximation by considering the iteration equation of many-Fermion wave-function through the system Hamiltonian propagator, and it is shown that by imposing the plane wave approximation for the struck particle it is possible to remove these ambiguities (the plane wave impulse approximation (PWIA)). Finally it is concluded that in order to get relevant result, one should be careful to perform the IA on the many-Fermion wave function to calculate the response function of the system, since the system response is obviously very sensitive to this quantity.