The retention of extracellular matrix proteins and angiogenic and mitogenic cytokines in a decellularized porcine dermis

Topical Collagen-Based Biomaterials for Chronic Wounds: Rationale and Clinical Application

“…In addition to modulation of proteolytic activity, 56 SIS provides a structural matrix and growth factors that may promote angiogenesis and cell migration. 76 The ECM research focus has recently swung heavily toward regenerative medicine with an emphasis on organ replacement. ECM modulates a wide variety of cell responses which are tissue dependent, that is, based on the derivation of the ECM (organ vs. organism), and cell dependent, that is, based on the cells expected to grow into the matrix (endothelial cells, fibroblasts, etc.).…”

Towards the development of a bioengineered uterus: Comparison of different protocols for rat uterus decellularization

“…Various techniques for decellularization and recellularization have been examined for pre-clinical interventions of miscellaneous tissues, e.g., small intestine [13,14], urinary bladder [15], heart valves [16], larynx [17], dermis [18], musculofascial tissue [19] and nerves [20,21]. Concerning the female internal genital tract, small patches of myometrial tissue were recently decellularized using a modified protocol that had been optimized for decellularization of blood vessels [22].…”

The “Pull-Over” Technique for Arthroscopic Superior Capsular Reconstruction

“…These processes are reported to exhibit more than 94% removal of DNA, therefore minimizing risks of immune and inflammatory response and adhesions. 6 We did not have any cases of infection or excessive inflammatory response. We do, however, recommend that ASCR should not be performed in the presence of any active infection or previous shoulder joint infection.…”