The revelation of glucose adsorption mechanisms on hierarchical metal–organic frameworks using a surface plasmon resonance sensor

Gumilar, Gilang; Chowdhury, Silvia; Shukri, Ganes; Patah, Aep; Nugraha, Nugraha; Henzie, Joel; Anshori, Isa; Kaneti, Yusuf Valentino; Yuliarto, Brian

doi:10.1039/d3tb00138e

Cited by 14 publications

(4 citation statements)

References 89 publications

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“…SPR is a powerful optical technique and one of the most attractive methods for surface-sensitive biomolecular interaction analysis and the real-time detection of various molecules [166]. It has the advantage of being able to analyze affinity and kinetics without labeling, and being able to directly use the characterization platform as a quantitative sensor.…”

Section: Other Types Of Sensorsmentioning

confidence: 99%

Research Progress of Nucleic Acid Detection Technology for Genetically Modified Maize

Luo,

Li,

Wang

et al. 2023

IJMS

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Genetically modified (GM) maize is one of the earliest GM crops to have achieved large-scale commercial cultivation globally, and it is of great significance to excel in the development and implementation of safety policy regarding GM, and in its technical oversight. This article describes the general situation regarding genetically modified maize, including its varieties, applications, relevant laws and regulations, and so on. From a technical point of view, we summarize and critically analyze the existing methods for detecting nucleic acid levels in genetically modified maize. The nucleic acid extraction technology used for maize is explained, and the introduction of traditional detection techniques, which cover variable-temperature and isothermal amplification detection technology and gene chip technology, applications in maize are described. Moreover, new technologies are proposed, with special attention paid to nucleic acid detection methods using sensors. Finally, we review the current limitations and challenges of GM maize nucleic acid testing and share our vision for the future direction of this field.

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Section: Other Types Of Sensorsmentioning

confidence: 99%

Research Progress of Nucleic Acid Detection Technology for Genetically Modified Maize

Luo,

Li,

Wang

et al. 2023

IJMS

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“…In 2023, Gumilar et al first investigated the role of metal–organic frameworks (MOFs) in SPR sensors. 25 The results showed that the layered metal-BDC functionalized SPR chip has higher sensitivity and a lower detection limit than bare gold only. And in the presence of other mixed interferents tested, Zr-BDC showed good selectivity for glucose in all cases.…”

Section: Introductionmentioning

confidence: 96%

Surface plasmonic biosensors: principles, designs and applications

Liu,

Fu,

Yang

et al. 2023

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“…Studies of the interactions of carbohydrates with specific blood proteins have been conducted, and low detection limits of below 0.01 mg mL −1 have been reached [19]. Lately, the detection of simple sugars with the use of SPR has been achieved in a good concentration range of millimoles, for such small-molecular target [20]. Finally, there are publications in which researchers conducted SPR studies of polymer and polysaccharide nanoparticles and their affinity to blood proteins such as heparin [21].…”

Section: Introductionmentioning

confidence: 99%

Study on Saccharide–Glucose Receptor Interactions with the Use of Surface Plasmon Resonance

Trzaskowski,

Drozd,

Ciach

2023

IJMS

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The aim of this study was to investigate the process of attachment of saccharide particles differing in degree of complexity to cell receptors responsible for transport of glucose across the cell membrane (GLUT proteins). This phenomenon is currently considered when designing modern medicines, e.g., peptide drugs to which glucose residues are attached, enabling drugs to cross the barrier of cell membranes and act inside cells. This study aims to help us understand the process of assimilation of polysaccharide nanoparticles by tumour cells. In this study, the interactions between simple saccharides (glucose and sucrose) and dextran nanoparticles with two species of GLUT proteins (GLUT1 and GLUT4) were measured using the surface plasmon resonance technique. We managed to observe the interactions of glucose and sucrose with both applied proteins. The lowest concentration that resulted in the detection of interaction was 4 mM of glucose on GLUT1. Nanoparticles were measured using the same proteins with a detection limit of 40 mM. These results indicate that polysaccharide nanoparticles interact with GLUT proteins. The measured strengths of interactions differ between proteins; thus, this study can suggest which protein is preferable when considering it as a mean of nanoparticle carrier transport.

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The revelation of glucose adsorption mechanisms on hierarchical metal–organic frameworks using a surface plasmon resonance sensor

Abstract: The gold layer on the surface plasmon resonance (SPR) sensor chip is tough to detect small molecules without using specific receptors, one of which is the glucose molecule. However, metal-organic...

Cited by 14 publications

References 89 publications

Research Progress of Nucleic Acid Detection Technology for Genetically Modified Maize

Research Progress of Nucleic Acid Detection Technology for Genetically Modified Maize

Surface plasmonic biosensors: principles, designs and applications

Study on Saccharide–Glucose Receptor Interactions with the Use of Surface Plasmon Resonance

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