The Rise of ST-Elevation Myocardial Infarction in Women of Northeast China

Abstract

The women of China’s Liaoning province display some morbidities in ways that defy medical explanation. Women have higher rates of hypertension, hypercholesterolemia, and metabolic syndrome than men, an anomaly for all three conditions. Most of these patients also suffer from Type 2 Diabetes Mellitus (T2DM) while there was a negative association between being female and T2DM for the rest of China. Each of these conditions can exist independently, but the increase in both their rates and congruence is a recent phenomenon. Stranger still is that Liaoning women are now presenting in hospital emergency departments with ST-Elevation Myocardial Infarction (STEMI), while diabetics predominantly suffer more benign Non-STEMI (NSTEMI) events. Confounding factors in any attempt to study this phenomenon include trace metals like manganese that have been shown to reduce systolic blood pressure in Asian men and raise it in Asian women. Some of the phenomenon may also be associated with the gene for Apolipoprotein 5, but its recent nature suggests other factors besides lipid profiles. Trace metals in the air, water, and diet of Liaoning province, or any urban environment, could play a role.

A Comparative Study of in hospital Complications among Diabetic Hypertensive Patients and Normal Blood Pressure Diabetic Patients Presented with Acute Myocardial Infarction

“…The higher complication rate of this study and its causes can be explained 16 . First, poor control of diabetes and hypertension in our patients, second, due to late clinical treatment due to ignorance of MI and poor logistical support, third, primary PCI in MI patients was considered late as primary PCI has higher efficacy than pharmacological improvement, and fourth higher Mortality among Asians [17][18] .…”