In the context of Industry 5.0, the concept of the Metaverse aligns with the vision of Web 4.0, representing a digital ecosystem where individuals and organizations collaborate in a human-centric approach to create personalized value. This virtual universe connects multiple interconnected worlds, enabling real-time interactions between users and computer-generated environments. By integrating technologies like artificial intelligence (AI), virtual reality (VR), and the Internet of Things (IoT), the Metaverse within Industry 5.0 aims to foster innovation and enhance productivity, efficiency, and overall well-being through tailored and value-driven solutions. Therefore, this entry explores the concept of the Metaverse in the context of Industry 5.0, highlighting its definition, evolution, advantages, and disadvantages. It also discusses the pillars of technological advancement, challenges, and opportunities, including its integration into manufacturing. The entry concludes with a proposal for a conceptual framework for integrating the human-centric Metaverse into manufacturing.