The Risk Factors for Portal Vein Thrombosis After Living Donor Liver Transplantation in Adults

Meta‐analysis and systematic review: Prevalence, graft failure, mortality, and post‐operative thrombosis in liver transplant recipients with pre‐operative portal vein thrombosis

“…Early (< 30 days) and late (≥30 days) PVT occurred in .71% and 1.33% of patients, respectively. In contrast to previous studies suggesting the risk of early re-thrombosis is greater than that of late re-thrombosis, 85,87 findings from our analysis instead suggest that the risk of re-thrombosis remains high throughout the post-operative period. As such, patients with pre-operative PVT could still benefit from the administration of prophylactic anticoagulation even in a delayed setting in addition to early prophylaxis, so as to address the risk of both early and late PVT.…”

“…However, a recent retrospective study reported a significantly higher rate of early graft loss among patients with higher grades of PVT. 9 Patients with pre-transplant PVT have generally been found to be at a heightened risk for re-thrombosis post LT, 85 predisposing these patients to graft failure and worsened overall survival. 86 In our analysis, the overall incidence of post-operative PVT was 1.94%.…”