The risk of post ERCP pancreatitis with and without sphincterotomy in patients undergoing biliary stent placement

Does endoscopic sphincterotomy reduce the risk of post‐endoscopic retrograde cholangiopancreatography pancreatitis after biliary stenting? A systematic review and meta‐analysis

“…Of these, five studies were randomized controlled trials . In addition, 12 observational studies (including two abstracts) were included in the present review …”

“…In two other studies, biliary stenting was carried out for either biliary obstruction or bile leak (Table ) . In one abstract, indication for biliary stenting was not specified . Majority of patients with biliary obstruction in RCT had distal CBD obstruction.…”

“…6,[9][10][11][12] In addition, 12 observational studies Digestive Endoscopy 2016; 28: 394-404 Sphincterotomy and pancreatitis 395 (including two abstracts) were included in the present review. 4,[13][14][15][16][17][18][19][20][21][22]28 A total of 2710 patients were enrolled in the analysis, which included 600 patients from RCT ( Fig. 1).…”

“…13,16 In one abstract, indication for biliary stenting was not specified. 22 Majority of patients with biliary obstruction in RCT had distal CBD obstruction. However, the overall proportion of patients with proximal bile duct obstruction was equal between the patients who had ES (22%) versus those without ES (21%) in RCT.…”