The risks and benefits of prophylactic aspirin in vascular disease and cancer

Evolving Concepts in the Primary Prevention of Cardiovascular Disease: Aspirin Then and Now

“…Of greater and more immediate clinical benefit are observational epidemiologic studies, as well as randomized trials, indicating that the benefits of aspirin and statins are at least additive [16]. Observational studies and randomized trials also suggest the potential of aspirin for the prevention and treatment of migraine [17], for delaying the progression of memory loss [18] and for the prevention of a variety of cancers, especially colorectal cancer [19]. For these and other cogent reasons, aspirin, which was termed the wonder drug of the 20th century, may become the wonder drug of the 21st century.…”