The Roche Immunoturbidimetric Albumin Method on Cobas c 501 Gives Higher Values Than the Abbott and Roche BCP Methods When Analyzing Patient Plasma Samples

Helmersson‐Karlqvist, Johanna; Flodin, Mats; Havelka, Aleksandra Mandic; Xu, Xiao Yan; Larsson, Anders

doi:10.1002/jcla.21921

Cited by 7 publications

(3 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Serum glucose (reference interval 4.11-6.05 mmol/L), C-reactive protein (CRP) (reference interval 1.5-50.00 mg/L), creatinine (reference interval 74.26-109.62 µmol/L), blood urea nitrogen (BUN) (reference interval 6.07-15.35 mmol/L), aspartate aminotransferase (AST) (reference interval 0.08-0.67 µkat/L) and alanine aminotransferase (ALT) (reference interval 0.08-0.68 µkat/L) levels were measured using the immunoturbidimetric method. 11 Serum sodium (reference 136-146 mmol/L) and potassium (reference interval 3.5-5.1 mmol/L) level values were determined with the ion-selective electrode (ISE) method. 12 All parameters were studied on an analyzer (COBAS c501, Roche Diagnostics, Basel, Switzerland) using their original commercial kits (Roche, Basel, Switzerland).…”

Section: Biochemical Analysismentioning

confidence: 99%

“…The neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), and systemic inflammation response index (SIRI) were also calculated as defined in the literature. [11][12][13] these data were analyzed using the independent samples t-test (p < 0.05). Nonparametric data were expressed as median (minimum-maximum), and to find out the differences between the study groups, these data were analyzed using the Mann Whitney U-test (p < 0.05).…”

Section: Biochemical Analysismentioning

confidence: 99%

See 1 more Smart Citation

Can Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?

Yüksel

Özdemır

Kısa

et al. 2021

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

View full text Add to dashboard Cite

Background Today, there is a need for new and independent additional advanced markers that can predict the prognosis of meningioma patients, postoperatively. The present study aimed to find out postoperative short-term prognostic markers in patients with meningioma using their demographic data and routine blood biochemistry findings evaluated preoperatively. Methods The Glasgow Coma Scale (GCS), and Glasgow Outcome Scale (GOS) scores of the patients were recorded. Additionally, preoperatively obtained serum glucose, C-reactive protein (CRP), sodium, potassium, creatinine, blood urea nitrogen, aspartate aminotransferase (AST), alanine aminotransferase, and hemoglobin level values, platelet, leukocyte, neutrophil, lymphocyte, eosinophil, basophil, and monocyte count results, erythrocyte sedimentation rate (ESR), neutrophil-lymphocyte ratio, platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) values were evaluated. Results In the present study, 23 operated patients with meningioma World Health Organization (WHO) grade 1 (17 females, 6 males) were included. Correlation test results revealed that the GCS score, platelet count, and serum potassium level values could directly predict the short-term prognosis of these patients. Additionally, these test results suggested that the lymphocyte, monocyte, and eosinophil count values, PLR, LMR, ESR, serum glucose, CRP, and AST level values could be indirect markers in predicting the short-term prognosis. However, likelihood ratio test results revealed that only monocyte count value, LMR value, and serum CRP level value could be the markers for prediction of the short-term prognosis. Conclusion At the end of the present study, it was concluded that the monocyte count value, LMR value, and serum CRP level value could be the best markers in predicting the short-term prognosis of the operated meningioma patients.

show abstract

Section: Biochemical Analysismentioning

confidence: 99%

Section: Biochemical Analysismentioning

confidence: 99%

Can Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?

Yüksel

Özdemır

Kısa

et al. 2021

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

View full text Add to dashboard Cite

show abstract

“…Overnight fasting biochemical evaluation included serum and 24-hour urinary calcium, serum albumin, ionized calcium, serum and 24-hour urinary phosphate, total alkaline phosphatase, bone alkaline phosphatase isoenzymes, glucose, insulin, total and HDL cholesterol, triglycerides, and creatinine. Biochemical parameters were assayed by routine methods (Roche modular platform, Roche Diagnostics, Mannheim, Germany); in particular, albumin was measured immunoturbidimetrically, providing measurements similar to those obtained by the bromocresol purple (BCP)-based method [5].…”

Section: 2mentioning

confidence: 99%

Symptomatic Hypercalcemia in Patients with Primary Hyperparathyroidism Is Associated with Severity of Disease, Polypharmacy, and Comorbidity

Aresta

Passeri

Corbetta

2019

International Journal of Endocrinology

View full text Add to dashboard Cite

Current primary hyperparathyroidism (PHPT) clinical presentation is asymptomatic in more than 90% of patients, while symptoms concern osteoporosis and rarely kidney stones. Here, we retrospectively investigated the prevalence of PHPT patients presenting with hypercalcemic-related symptoms (HS-PHPT) as cognitive impairment, changes in sensorium, proximal muscle weakness, nausea and vomiting, constipation, and severe dehydration, in a single center equipped with an emergency department and described their clinical features and outcome in comparison with a series of asymptomatic PHPT out-patients (A-PHPT). From 2006 to 2016, 112 PHPT patients were consecutively diagnosed: 16% (n = 18, 3M/15F) presented with hypercalcemic-related symptoms. Gastrointestinal symptoms occurred in 66% of HS-PHPT patients and cognitive impairment in 44%; one woman experienced hypertensive heart failure. Two-thirds of HS-PHPT patients were hospitalized due to the severity of symptoms. Comparing the clinical features of HS-PHPT patients with A-PHPT patients, no gender differences were detected in the two groups, while HS-PHPT patients were older at diagnosis (71 (61–81) vs. 64 (56–74) years, P=0.04; median (IQR)). HS-PHPT patients presented higher albumin-corrected calcium levels (12.3 (11.3–13.7) vs. 10.6 (10.3–11.3) mg/dl, P<0.001); 4 HS-PHPT presented corrected calcium levels >14 mg/dl. Serum PTH levels and total alkaline phosphatase activity were higher in HS-PHPT. Reduced kidney function (eGFR < 45 ml/min) was prevalent in HS-PHPT patients (42% vs. 5%, P=0.05). No differences in kidney stones and osteoporosis were detected, as well as in the rates of cardiovascular comorbidities and main cardiovascular risk factors. HS-PHPT patients had an age-adjusted Charlson Comorbidity Index higher than that of the A-PHPT patients and were on chronic therapy with a greater number of medications than A-PHPT patients. In conclusion, hypercalcemic-related symptoms occurred in 16% of PHPT patients. Risk factors were severity of the parathyroid tumor function, multimorbidity, and polypharmacy.

show abstract

Is capillary zone electrophoresis a suitable method for estimating serum albumin: A comparison of four methods

Padelli

Leven

Reun³

et al. 2018

Clinica Chimica Acta

View full text Add to dashboard Cite

The Roche Immunoturbidimetric Albumin Method on Cobas c 501 Gives Higher Values Than the Abbott and Roche BCP Methods When Analyzing Patient Plasma Samples

Abstract: The Roche immunoturbidimetric albumin method gives clearly higher values than the Abbott and Roche BCP methods when analyzing fresh patient samples. The differences between the two methods were similar at normal and low albumin levels.

Cited by 7 publications

References 27 publications

Can Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?

Can Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?

Symptomatic Hypercalcemia in Patients with Primary Hyperparathyroidism Is Associated with Severity of Disease, Polypharmacy, and Comorbidity

Is capillary zone electrophoresis a suitable method for estimating serum albumin: A comparison of four methods

Contact Info

Product

Resources

About