Horizontal well and hydraulic fracturing have been proved to be an effective technology to increase the recovery of shale gas reservoirs. During a fracturing treatment, a pair of main fractures is firstly generated perpendicular to wellbore direction.As fluids continue to be pumped, more micro-sized fractures are generated near the main fractures and form a fracture network. This micrometer sized fracture network has much more contact area with the matrix than traditional single pair of fracture, and holds majority of the productivity potential of shale gas. Friction reducer (FR) is one of the primary components of this fracturing fluid. It is used to decrease the flowing friction in the pipeline. Flow loop tests in lab and field applications have addressed this issue thoroughly. However, the flow characteristics of friction reducer solution in microfractures are not clear. This study used capillary tubes to represent microchannel, and the flow behavior of FR solution in these microchannels was systematically studied.With FR solution flowing in the microchannels at various velocities, different FR concentration, microchannel size, and microchannel surface wettability impact on the FR flow behavior was investigated in detail. It is found that the friction reducer is a slight shear thinning fluid with properties that can be expressed by a power-law equation. Its residual resistance factor to water was also specified, which is closely related with the fluid flowback. Finally, the experimental results were compared with the data in a flow loop experiment. Its flow behavior resistance was considered found to be increased in microchannel rather than decreased to be different from that in the centimeter sized tubings.