The Role of Anesthetic Selection in Perioperative Bleeding

Abstract

Perioperative bleeding is one of the major comorbidities associated with surgery. While anesthesia is a critical component to perform surgery, a number of clinical studies supported the contribution of anesthetic drugs to perioperative bleeding. Here, we reviewed the literature on this topic including the underlying mechanism and discussed the future direction on coagulation research in anesthesia.

Hubungan Kegawatdaruratan dengan Teknik Anestesi pada Plasenta Akreta di RSUP H. Adam Malik Medan

“…Pada kasus plasenta akreta, anestesi neuraksial tidak selalu dikontraindikasikan dan dari beberapa penelitian teknik anestesi neuraksial dapat mengurangi perkiraan kehilangan darah pada pembedahan untuk plasenta akreta sederhana. 3,5,6 Pada operasi sesar, anestesi neuraksial secara luas dianggap lebih aman daripada anestesi umum, tetapi masih terbatasnya bukti untuk mengkonfirmasi kesan klinis ini. Risiko kematian ibu dengan anestesi umum dilaporkan 17 kali lipat lebih besar dibandingkan dengan anestesi neuraksial walaupun komplikasi serius dari anestesi umum, termasuk intubasi yang gagal, kesadaran intraoperatif, dan aspirasi fatal isi lambung, jarang terjadi.…”

General anesthesia with nerve blocks for a patient with femoral fracture and essential thrombocythemia: a case report

“…Platelets are the primary cell type involved in hemostasis, and current data suggest that different anesthetics impact on hemostatic function and surgical bleeding. 2 Therefore, the high platelet count of patients with ET causes concerns for anesthesiologists during surgery. However, because few studies have used thromboelastography platelet mapping or platelet aggregation assays to determine the effects of anesthetics on platelets, the results of studies that investigated the impact of regional versus general anesthesia were mixed.…”