The role of aortic valve calcium in the detection of aortic stenosis: An echocardiographic study

Rubler, Shirley; King, Marjorie L.; Tarkoff, David M; Dolgin, Martin; Reitano, John M.; Schreiber, Jonathan

doi:10.1016/0002-8703(85)90249-2

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…al. extended these observations by using echocardiography to grade aortic valve calcium in 153 males with aortic valve disease [ 8 ]. The presence of moderate to severe aortic valve calcium identified those with severe AS confirmed by cardiac catheterization.…”

Section: Discussionmentioning

confidence: 99%

Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Shavelle

Buljabasic

Takasu

et al. 2006

Cardiovasc Ultrasound

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The severity index is a new echocardiographic measure that is thought to be an accurate indicator of aortic leaflet pathology in patients with AS. However, it has not been validated against cardiac catheterization or Doppler echocardiographic measures of AS severity nor has it been applied to patients with aortic sclerosis. The purposes of this study were to compare the severity index to invasive hemodynamics and Doppler echocardiography across the spectrum of calcific aortic valve disease, including aortic sclerosis and AS. 48 patients with aortic sclerosis and AS undergoing echocardiography and cardiac catheterization comprised the study population. The aortic valve leaflets were assessed for mobility (scale 1 to 6) and calcification (scale 1 to 4) and the severity index was calculated as the sum of the mobility and calcification scores according to the methods of Bahler et al. The severity index increased with increasing severity of aortic valve disease; the severity indices for patients with aortic sclerosis, mild to moderate AS and severe AS were 3.38 ± 1.06, 6.45 ± 2.16 and 8.38 ± 1.41, respectively. The aortic jet velocity by echocardiography and the square root of the maximum aortic valve gradient by cardiac catheterization correlated well with the severity index (r = 0.84, p < 0.0001; r = 0.84, p < 0.0001, respectively). These results confirm that the severity index correlates with hemodynamic severity of aortic valve disease and may prove to be a useful measure in patients with aortic sclerosis and AS.

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Section: Discussionmentioning

confidence: 99%

Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Shavelle

Buljabasic

Takasu

et al. 2006

Cardiovasc Ultrasound

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“…In fact, roughly 50% of patients with aortic sclerosis are also affected by mitral valve sclerosis 8 . For many years it has been thought that aortic valve sclerosis carries a good prognosis as compared to aortic stenosis 9 . On the contrary, in patients with congenital bicuspid aortic valve, it is possible to identify aortic sclerosis in the second decade, and often it progresses to stenosis with age and calcium on aortic valve noted in the fourth decade 10 .…”

mentioning

confidence: 99%

“…8 For many years it has been thought that aortic valve sclerosis carries a good prognosis as compared to aortic stenosis. 9 On the contrary, in patients with congenital bicuspid aortic valve, it is possible to identify aortic sclerosis in the second decade, and often it progresses to stenosis with age and calcium on aortic valve noted in the fourth decade. 10 Moreover, aortic valve calcification has also been noticed in patients affected by the atherosclerotic process involving the tricuspid valve.…”

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confidence: 99%

Aortic Valve Sclerosis: Is It a Cardiovascular Risk Factor or a Cardiac Disease Marker?

Palmiero¹,

Maiello²,

Passantino³

et al. 2007

Echocardiography

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Aortic sclerosis is associated with a higher prevalence of left ventricular hypertrophy, ventricular arrhythmias, myocardial infarction, and systolic heart failure, while the prevalence of cardiovascular risk factors is not different between aortic sclerosis patients and controls. Hence, aortic sclerosis represents a cardiac disease marker useful for early identification of high-risk patients beyond cardiovascular risk factors rate.

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Modifying the Natural History of Aortic Valve Stenosis

Heuvelman

Rajamannan

Takkenberg

2012

Cardiac Valvular Medicine

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The role of aortic valve calcium in the detection of aortic stenosis: An echocardiographic study

Cited by 6 publications

References 15 publications

Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Validation of the severity index by cardiac catheterization and Doppler echocardiography in patients with aortic sclerosis and stenosis

Aortic Valve Sclerosis: Is It a Cardiovascular Risk Factor or a Cardiac Disease Marker?

Modifying the Natural History of Aortic Valve Stenosis

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