The role of apoptosis in cisplatin-induced ototoxicity in rats

Effects of subchronic inhalation exposure to an organophosphorus insecticide compound containing dichlorvos on wistar rats’ otoacoustic emissions

“…The sample size was based on previous studies, using the variability in the responses to the auditory parameters evaluated in rats exposed to the ototoxic agent cisplatin as a positive control. 19 …”

Ototoxicity of cypermethrin in Wistar rats

“… 8 Moreover, most of the researches that related pesticides with hearing loss are case reports or human studies exposed to noise machinery and to other factors that also can cause hearing damage. 8 , 10 , 12 , 13 , 14 , 15 , 16 , 17 , 18…”

Mechanisms of cisplatin ototoxicity: theoretical review

“…Freitas et al 60 investigated the role of apoptosis in cisplatin-induced cochlear injury using a male Wistar rat model. The animals were divided into eight groups distinguished by differing cisplatin dose, administration mode, and assessment type and timing (DPOAE and brainstem evoked auditory potentials were used).…”